摘要
为研究颇利肝胶囊（ＰＬＧＣ）对小鼠免疫功能的影响，分别观察了ＰＬＧＣ对小鼠巨噬细胞吞噬功能和血清溶血素的影响，以及对巨噬细胞分泌白介素－１、白介素－２的影响。结果：实验组吞噬指数和吞噬系数均较对照组明显升高（Ｐ＜０．０１）；５０ｍｇ／ｋｇ和１００ｍｇ／ｋｇ实验组的半数溶血值较对照组明显升高（Ｐ＜０．０１）；实验组ＰＬＧＣ可恢复由环磷酰胺所抑制的小鼠巨噬细胞分泌白介素－１的能力；实验组较对照组显著提高小鼠脾细胞生成白介素－２的能力（Ｐ＜０．０５～０．０１）。结果显示。
This study aimed at the immune response of mice to Po Li Gan Capsule (PLGC). The effects of PLGC on phagocytosis of phagocyte, on serum hemolysin, and on IL 1, IL 2 in mice were investigated. The results showed that the coefficient and index of phagocytosis obviously increased in the experiment group, compared with that in the control group ( P<0.01 ); the serum hemolysin in the experiment group increased too ( P<0.01) . The results also showed that PLGC could restore the capacity of macrophage for secreting IL 1 that had been inhibited by cyclophosphamide and PLGC could enhance the release of IL 2 from spleen cell in the experiment group ( P<0.05 0 01). These suggest that PLGC enhances both cellular and humoral immunity function in mice.
出处
《华西医科大学学报》
CAS
CSCD
1999年第1期101-103,共3页
Journal of West China University of Medical Sciences
