摘要
目的探讨综合心理治疗对首发青少年抑郁症的临床疗效。方法将147例首发青少年抑郁症患者随机分为A组40例、B组37例、C组37例、D组33例；A组顿服盐酸氟西汀治疗，B组给予综合心理治疗；C组给予认知行为治疗，D组顿服盐酸氟西汀胶囊联合综合性心理治疗。观察8周。于治疗前及治疗第2周、4周、8周末采用汉密顿抑郁量表评定临床疗效，副反应量表评定不良反应。结果四组患者治疗2周末起，汉密顿抑郁量表总分均较治疗前有显著下降（P〈0．01）；A组治疗第4周、8周末汉密顿抑郁量表总分减分率显著低于D组（P〈0．05或0．01）；B组治疗第2周、4周末总分减分率显著高于C组（P〈0．01）。治疗8周末，4组痊愈率、显效率均无显著性差异（P〉0．05）。结论对首发青少年抑郁症患者而言，综合心理治疗优于认知行为治疗，应用盐酸氟西汀联合综合心理治疗起效更快，效果更为显著。
Objective To explore the effect of integrated psychotherapy on adolescent patients with first-episode depressive disorder. Methods Fluoxetine wereused in treated 40 cases, integrated psychotherapy were used in treated 37 cases, cognitive behavioral therapy（CBT） were used in treated 37 cases, and fluoxetine combined integrated psychotherapy were used in treated 33 cases. Hamilton depression rating scale fordepression（HAMD） were used to evaluated the efficacy before treatment and at the 14th ,28th and 56th. Results All the total scores of HAMD among the four groups decreased significantly at the 14th, 28th and 56th（P〈0.01）. The score of HAMD in fluoxetine corn-bined integrated psychotherapy group decreased more quickly than that in fluoxetine treatment group at the 28th and 56th（p〈0. 05）,integrated psychotherapy decreased the score of HAMD more quickly than CBTdid at the 14th, 28th （P〈0.01）. There were no significant difference in cure rate and markedly effective rate among the four groups（P〉0.05）. Conclusion To cure the adolescent depression,integrated psyehothera-py is better than CBT, and fluoxetine combined integrated psychotherapy is more effective.
出处
《临床心身疾病杂志》
CAS
2010年第4期331-333,共3页
Journal of Clinical Psychosomatic Diseases
基金
基金项目：广东省社会科学规划课题项目资助（编号2005SXY003）
