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梅毒患者外周血Th1/Th2类细胞因子mRNA表达及临床意义 被引量:1

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摘要 为探讨Th1和Th2类辅助性T细胞在梅毒发病中的作用,我们以IFN-γ和/L-2代表Th1类细胞因子,IL-4和IL—10代表Th2类细胞因子,通过RT—PCR方法检测了一、二期梅毒患者和正常对照组外周血单个核细胞(PBMC)中Th1和Th2类细胞因子mRNA表达水平。
出处 《中国麻风皮肤病杂志》 2010年第7期530-531,共2页 China Journal of Leprosy and Skin Diseases
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  • 1Van Voorhis WC, Barrett LK, Koelle DM, et al. Primary and secondary syphilis lesions contain mRNA for Thl cytokines. J Infect Dis, 1996, 173(2): 491-495.
  • 2Shin JL, Chung KY, Kang JM, et al. The effects of Treponema pallidum on human dendritic cells.Yonsei Med J, 2004, 45 (3): 515-522.
  • 3Podwinska J, Lusiak M, Zaba R, et al. The pattern and level of cytokines secreted by Thl and Th2 lymphocytes of syphilitic patients correlate to the progression of the disease. FEMS Immunol Med Microbiol, 2000, 28( 1 ): 1-14.
  • 4Banchereau J, Briere F, Caux C, et al. Immunobiology of dendritic cells. Annu Rev Immunol, 2000, 18:767-811.
  • 5Bouis DA, Popova TG, Takashima A, et al. Dendritic cells phagocytose and are activated by Treponema pallidum. Infect Immun, 2001, 69( 1 ): 518-528.
  • 6Centers for Disease Control and Prevention. Sexually transmitted diseases treastment guidelines. MMWR Recomm Rep, 2006, 55 (RR-11): 1-94.
  • 7Van Voorhis WC,Barret LK,Koelle DM,et al.Primary and secondary syphilis lesions contain mRNA for Th1 cytokines[J].J Infect Dis,1996,173(2):491 -495.
  • 8Eoechling N,Schluepen Em,Soyer HP,et al.Molecular detection of treponema pallidum in secondary and tertiary syphilis[J].Br J Dermatol,1997,136:683-686.
  • 9Fitegerald TJ.The Th1/Th2-like switch in syphilis infection:is it detrimental?[J].Infect Immun,1992,60:3475-3479.
  • 10Podwinska I,Lusiak M,Eaba R,et al.The pattern and level of cytokines secrected by Th1 and Th2 lymphocytes of syphilitic patients correlate to the progression of the disease[J].FEMS-Zmmunol-Med-Microbiol,2000,28(1):1 -4.

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