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含氮杂冠醚和核酸碱基双亲聚合物的合成及性能 被引量：4

Synthesis and Property of an Amphiphilic Polymer Containing Nucleobases and Aza-crown Ethers
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摘要 设计合成了含氮杂冠醚和胸腺嘧啶的双亲聚合物聚[N,N-二乙氧基-1,10-二氮杂-18冠-6-5-甲基-胸腺嘧啶-异酞酸酯](PCTSE).用SEM观测到其在水溶液中自发聚集成直径为150～220nm的纳米球;用动态光散射测得PCTSE纳米球水溶液的粒径分布主要集中在130～240nm,用FTIR研究了PCTSE/腺嘌呤中胸腺嘧啶与底物腺嘌呤的分子识别作用,结果表明,聚合物中胸腺嘧啶环上C4O伸缩振动峰从1670cm-1位移至1664cm-1,表明胸腺嘧啶与腺嘌呤间形成了氢键.变温红外光谱表明,该峰又随温度的升高逐渐向高波数位移,最后位移到识别前的1670cm-1处,表明所形成的氢键断裂. An amphiphilic polymer containing thymine and aza-crown ethers,poly-{ [N,N-bis（ 2-ethoxy） -1, 10-diaza-18-crown-6][5-methylene-（ 1-thymine） ]sophthaloyl ester} （ PCTSE） ,was synthesized. The SEM morphology observed via indicates that the amphiphilic PCTSE polymer self-organized into diameters of about 150—220 nm nanospheres in dilute aqueous solution spontaneously. The sizes of PCTSE nanospheres in dilute aqueous solution determined by DLS are mainly dispersed at 130—240 nm. The molecule recognition based on hydrogen bond between thymine of polymer and adenine substrate in PCTSE/adenine nanospheres was studied. After recognition the C4 O stretching vibration at 1670 cm -1 of thymine of polymer shifted to 1664 cm -1, which implied the formation of hydrogen bonds between thymine and adenine. The study on variable temperature FTIR show that the peak gradually shifted back to the position at 1670 cm -1,which indicates that the Hbond was broken.
作者 张瑀健 何振峰 李国文
机构地区 吉林大学超分子结构与材料国家重点实验室
出处 《高等学校化学学报》 SCIE EI CAS CSCD 北大核心 2010年第7期1456-1460,共5页 Chemical Journal of Chinese Universities
基金 国家自然科学基金(批准号:20874037 20674025)资助
关键词 双亲聚合物 氮杂冠醚 核酸碱基 纳米球 分子识别 Amphiphilic polymer Aza-crown ether Nucleobase Nanosphere Molecular recognition
分类号 O631 [理学—高分子化学]
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参考文献17

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同被引文献27

  • 1王刚,王宝凤,李文,陈皓侃,李保庆.亚临界水脱除煤中硫的实验研究[J].燃料化学学报,2005,33(5):630-632. 被引量：2
  • 2郝宇,齐庆杰,周新华,吴宪.燃煤过程中硫析出特性的影响因素研究(Ⅱ)[J].矿业快报,2005,21(10):16-19. 被引量：7
  • 3许招会,廖维林,刘德永.Williamson反应合成二甘醇二甲醚的研究[J].化学世界,2006,47(7):417-419. 被引量：4
  • 4刘粉荣,李文,李保庆,陈皓侃.氧化性气氛下流化床中煤的热解脱硫及硫的分布[J].燃料化学学报,2006,34(4):404-407. 被引量：18
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引证文献4

二级引证文献1

高等学校化学学报
2010年 第7期

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