摘要
目的了解近年住院肺结核病人对常用的6种抗结核药物的耐药情况。方法回顾性分析太原市结核病医院2007-04~2009-11收治住院的575例肺结核病人中痰结核分枝杆菌的耐药状况。结果 575例病人中,非结核分枝杆菌7例,人型肺结核和牛型肺结核共568例,568例中有288例耐药(总耐药率50.7%),耐多药者96例(16.9%)。耐单药率从高到低依次为链霉素,异烟肼,利福平,对氨基水杨酸钠,丙硫异烟胺,乙胺丁醇。结论目前肺结核的耐药率仍高,控制结核病,任重道远。
Objective To investigate the drug resistance of six anti-TB drugs in hospitalized tuberculosis patients in recent years. Methods Drug resistance in sputum Mycobacterium tuberculosis was retrospectively analyzed in patients hospitalized in Taiyuan Tuberculosis Hospital from April 2007 to November 2009. Results Of 575 cases,there were 7 cases of non-tuberculosis mycobacteria,and 568 cases of human and bovine pulmonary tuberculosis. The total resistance rate was 50. 7% ( 288 /568) ,and the multidrug-resistant rate was 16. 9% ( 96 /568 ) . The resistance rate from high to low in order was streptomycin,isoniazidnm,rifampin,para-aminosalicylic acid,prothionamide,and ethambatal. Conclusion The drug resistant rate is still high against tuberculosis,and to control TB is still a long way to go.
出处
《山西医科大学学报》
CAS
2010年第7期634-636,共3页
Journal of Shanxi Medical University
关键词
结核
结核分枝杆菌
耐药
tuberculosis
Mycobacterium tuberculosis
drug resistance