摘要
目的：观察人体感染人肉孢子虫（Ｓａｒｃｏｃｙｓｔｉｓｈｏｍｉｎｉｓ）的孢子囊排放情况和临床表现。方法：志愿者通过生食含人肉孢子虫包囊的牛肉而感染。１名吞食自然感染的黄牛横纹肌内人肉孢子虫包囊约１５６７个，２名分别吞食实验感染的水牛肌肉中的人肉孢子虫包囊各约１４７４０个。用硫酸锌离心漂浮法逐日粪检。结果：３名志愿者分别于感染后ｄ１１～４０、ｄ１２～２３和ｄ１０～３０粪中排出成熟孢子囊和卵囊，于ｄ１８、ｄ１４和ｄ１４达到排出高峰。并于感染后１ｗｋ～４ｗｋ出现腹痛、腹胀、腹泻和嗜酸性粒细胞增加。未经服药，２９ｄ内自愈。结论：人体感染人肉孢子虫后均出现消化道症状，于ｄ１０～１２粪中开始排出孢子囊和卵囊，持续排出时间为１１ｄ～２９ｄ。
AIM: To investigate the excretion of sporocysts and clinical manifestations in humans experimentally infected of Sarcocystis hominis . METHODS:Three volunteers were infected by eating raw beef containing cysts of S. hominis . One ingested about 1 567 cysts in skeletal muscles of a naturally infected cattle; two volunteers each ingested about 14 740 cysts from an experimentally infected water buffalo meat. Fecal examination by zinc sulfate flotation method was conducted daily since d 4 postinfection (pi). RESULTS:Free sporocysts and oocysts were found in their faeces from d 11～40 , d 12～23 ,d 10～30 pi , and peaked at d 18 , d 14 ,d 14 . All of them presented clinical symptoms such as abdominal pain, distension, watery diarrhea and eosinophilia 1 wk～4 wk pi and were spontaneously cured within 29 days pi without taking any medicine. CONCLUSION: All the experimentally infected persons had gastrointestinal symptoms and passed sporocysts and oocysts in faeces 10～12 days after infection and persisted for 11～29 days.
出处
《中国寄生虫学与寄生虫病杂志》
CAS
CSCD
北大核心
1999年第1期25-27,共3页
Chinese Journal of Parasitology and Parasitic Diseases
基金
国家自然科学基金
关键词
人肉孢子虫
实验感染
孢子囊
临床症状
血象
Sarcocystis hominis , experimental infection, sporocyst, clinical symptoms, hemogram
