摘要
目的:探讨原发性十二指肠乳头周围癌生物学行为与治疗应取的原则。方法:选取28例经内镜活检,手术探查和术后病理学证实的原发性十二指肠乳头周围癌,通过对其肿瘤的组织学类型、病理学类型与其转移等生物学特征的分析,研究与手术治疗方法应取的原则。结果:原发性十二指肠乳头周围癌主要病理学类型是息肉菜花型(93 ％),组织学类型主要为乳头状腺癌(75％),其转移部位依次为肠壁外、胰头十二指肠周、肠内、肝及远处淋巴结。手术治疗方法中:胰十二指肠切除术22例;短路术4例;1例局部切除术。结论:原发性十二指肠乳头周围癌主要是息肉菜花型乳头状腺癌,其转移可在各个层次进行,与肿瘤大小及病理学类型无关,胰十二指肠切除术是最为合理的根治性手术方法。
Purpose: To discuss the correlation between the biological behavior of primary duodenal papma penpneral carcinoma and the treatment. Methods: 28 cases of primary duodenal papilla peripheral carcinoma were selected, which were confirmed by endoscopic biopsy, exploratory laparotomy and postop-erative pathology. By analysis the biological features of the historical types, pathological types and spread methods, this tumor biological behavior features and treatment principle were studied. Results: The mainly pathological type of primary duodenal papilla peripheral carcinoma was a polypoid cauliflower(93%), his-tology type was a papilla adenocacinoma (75%). Metastasis location was out intestinal wall, around the head of pancreatoduodenal, in-intestinal, liver and beyond. In operations, pancreatoduodenectomy was 22 cases, by-pass 4, local resection 1. Conclusion: Primary duodenal papilla peripheral carcinoma mainly was the polypoid cauliflower papilla adenocacinoma and it might spread in each administrative levels of intestinal tracts, which was no relationship with the tumors size and pathology. Pancreatoduodenectomy was the most reasonable radical cure method.
出处
《临床消化病杂志》
1999年第1期7-8,共2页
Chinese Journal of Clinical Gastroenterology
关键词
原发性
十二指肠
乳头周围癌
生物学行为
治疗
Primary duodenal papilla peripheral carcinoma Biological behavior Treatment
