摘要
目的:探讨乙型肝炎肝硬化患者的发生模式及其相关因素。方法:回顾性分析住院确诊为乙型肝炎肝硬化的502例患者临床资料。结果:502例患者中,男女比例为4.02:1,31～60岁年龄阶段的乙型肝炎肝硬化的分布频率最高(74.3%),发病年龄与有无HBV感染家族史有相关性(P<0.05),而发病时间与有无HBV感染家族史无相关性;病毒复制状态以HBeAg阴性、HBVDNA阴性为多(58.0%),与抗病毒治疗有关;大多数肝硬化患者隐匿型发病(65.7%),随访不及时所占比例最高(67.1%),主客观原因分析中,患者保健知识缺乏所占比例最高(73.3%)。结论:乙型肝炎肝硬化患者以男性居多,病毒非复制状态为主,大部分患者隐匿性起病,患者保健知识缺乏,随访不及时是导致肝硬化发生的主要原因。
Objective：To explore the occurring model and the correlated factors of hepatitis B cirrhosis. Methods：We retrospectively studied the clinical features of 502 in-patients with hepatitis B cirrhosis. Results ： Among all the patients, the ratio of male / female was 4.02：1 ,the highest distribution frequency of age was 31-60 years old. The family history was correlated with the occurring age of hepatitis B cirrhosis （P〈0.05）, and not correlated with the occurring time （/9〉0.05）. The models of the detected virus were almost negative HBeAg and HBV DNA（57.97%）,which was related to anti-virus treatment. The occurring model of hepatitis B cirrhosis was occult type（65.74%）. The ratio of not in time follow-up was up to 67.13%. Among all of subjective and objective reasons,the ratio of the lack of health care knowledge was the highest, which was up to 73.31%. Conclusion：The clinical features of the patients with hepatitis B cirrhosis are common in males with negative HBV DNA. The occurring model is occult, which is the major reason that the patients do not follow-up in schedule and lack for health care knowledge.
出处
《现代医药卫生》
2010年第15期2263-2264,共2页
Journal of Modern Medicine & Health
关键词
乙型肝炎肝硬化
发生模式
相关因素
临床调查
Hepatitis B cirrhosis
Occurring model
Correlated factors
Clinical investigation
