摘要
目的：探讨骨的硬纤维瘤合理的外科治疗方法。方法：８例骨的硬纤维瘤患者，７例接受外科治疗（３例囊内切除、植骨及骨水泥填充，４例行广泛切除，人工假体置换）。结果：３例囊内切除中，除１例股骨下端３次复发后，恶变为骨肉瘤，术后２年半死于肺转移。余随访１～１２年，肿瘤无复发，邻近关节活动好。结论：骨的硬纤维瘤虽然是一种良性的肿瘤，但是具有较强的侵袭性，单纯行囊内切除，文献报道复发率可达５０％。因此。
Purpose:
Desmoplastic fibroma of bone is a rare benign tumor of bone. Its histopathologic feature is
similar to desmoid fibroma of soft tissue, and it has strong invasiveness and easy to recur.
Methods: The authors report on 8 cases treated by wide excision from 1986 to 1998 including 5
males and 3 females, with an average age of 28 years. The common site of the tumor was at
the epiphyseal end of the long bone.All the patients experienced local pain or a mass for a
relatively long time. Results: Surgery was not performed in one case with a huge mass and
multiple lesions. Seven patients were treated by operation including 3 intracapsular excision
and four wide excision. One of the three patients with tumor intracapsularly excised tumor
recurred 3 times and finally turned into osteosarcoma and died of lung metastasis.There was
no recurrence observed in four cases of wide excision and prosthesis. Conclusion: Wide
excision is the treatment of choice. Although desmoplastic fibroma of bone is considered as
benign tumor but its recurrence rate is about 50%after intracapsular excision. If wide excision is
not feasible, thorough curettage of the tumor followed by alcohol or liquid nitrogen deactivation
of tumor cavity is recommended.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
1999年第2期133-136,共4页
Chinese Journal of Clinical Oncology
关键词
骨肿瘤
硬纤维瘤
外科手术
Desmoplastic fibroma of boneTreatment Wide
excision
