摘要
目的对非肿块样强化与肿块样强化乳腺癌的动态增强磁共振成像(DCE-MRI)特征进行比较。方法收集269例经穿刺活检证实为乳腺癌,且在化疗前或手术前接受乳腺MRI检查的病例。根据强化类型分为肿块样强化病变组及非肿块样强化病变组,比较两组动态增强参数差异性。结果 269例乳腺癌患者中,非肿块样强化28例(10.41%),肿块样强化241例(89.59%)。50.00%非肿块样强化乳腺癌增强后晚期达到强化峰值,而81.74%肿块样强化乳腺癌早期即达强化峰值(P<0.001)。39.29%非肿块样强化乳腺癌呈流入型曲线,42.86%呈流出型曲线;75.93%肿块样强化乳腺癌呈流出型时间-信号强度曲线,仅9.13%呈流入型曲线。两种强化类型病变的流出率、信号增强比(SER)亦存在统计学差异。结论与肿块样强化乳腺癌比较,非肿块样强化乳腺癌倾向于增强后缓慢强化、呈现流入型时间信号强度曲线。
Objective To compare dynamic characteristics of MRI between non-mass-like and mass-like enhancement of breast cancer,in order to confirm the difference between the two enhancement patterns of dynamic contrast-enhanced magnetic resonance imaging （DCE-MRI） in breast cancer. Methods Totally 269 patients with confirmed breast cancer underwent breast MR before treatment,and the dynamic characteristics of MRI were collected. The patients were grouped into the non-mass-like enhancement group and the mass-like enhancement group,and comparisons in dynamic parameters were made between the two groups. Results Totally 28 patients manifested as non-mass-like enhancement （10.41%） and 241 of mass-like enhancement （89.59%）. Half of non-mass-like patients achieved peak enhancement in the late period after contrast material was injected,while 81.74% of mass-like enhancements showed this sign in the early period （P〈0.001）. Significantly larger part of non-mass-like enhancements （39.29%） showed a resistant type curve,and 42.86% in a washout type,while only 9.13% of mass-like enhancements in a resistant type,most of them in a washout type （75.93%）. Washout rate and signal enhancement ratio （SER） of non-mass-like enhancements were significantly different from those of mass-like ones. Conclusion Compared with mass-like enhancement,breast cancer of non-mass-like enhancement tends to show a slow enhancement in a resistant type on dynamic MRI. When dynamic characteristics are explored in the researches of MRI with breast cancer,they should be analyzed separately according to different enhancement patterns.
出处
《中国医学影像技术》
CSCD
北大核心
2010年第7期1258-1261,共4页
Chinese Journal of Medical Imaging Technology
基金
国家重点基础研究发展计划(973项目)(2006CB705076)
关键词
乳腺癌
磁共振成像
非肿块样强化
肿块样强化
Breast neoplasms
Magnetic resonance imaging
Non-mass-like enhancement
Mass-like enhancement
