摘要
目的比较老年和非老年健康人、反流性食管炎患者食管运动功能的异同。方法应用微气囊法对３０例老年健康人、１９７例非老年健康人、３０例老年反流性食管炎患者、４５例非老年反流性食管炎患者食管运动功能进行检测。结果（１）老年健康人食管下括约肌（ＬＥＳ）松弛时间为（８．１±０．８）秒，长于非老年健康人的（７．１±１．０）秒（Ｐ＜０．０１），食管蠕动波压力和食管上括约肌压力〔（４０．５±２．９）ｍｍＨｇ和（４８．７±１８．１）ｍｍＨｇ，１ｍｍＨｇ＝０．１３３ｋＰａ〕低于非老年健康人的（４５．０±１０．５）ｍｍＨｇ和（５６．１±２１．２）ｍｍＨｇ（Ｐ＜０．０１），同步收缩波发生率较非老年健康人增多（Ｐ＜０．０１）；（２）老年反流性食管炎组ＬＥＳ松弛时间〔（１０．８±１．１）秒〕延长和食管蠕动波压力〔（３３．２±２．９）ｍｍＨｇ〕降低比非老年组〔（９．２±３．７）秒、（４０．３±６．３）ｍｍＨｇ〕更明显（均为Ｐ＜０．０１）。结论（１）老年健康人有食管运动功能障碍；（２）老年反流性食管炎患者食管运动障碍比非老年患者明显。
Objective To study the differences of esophageal motility in healthy elderly (HE) and non elderly healthy subjects(NEHS), elderly and non elderly patients with reflux esophagitis (ERE, NERE). Methods Esophageal motility was investigated by multi spot balloon probe in 30 HE, 197 NEHS, 30 ERE and 45 NERE. Results (1)In HE, the time of lower esophageal sphincter (LES) relaxation was (8 1±0 8)second. It was longer than that in NEHS (7 1±1 0)second ( P <0 01).The pressure of esophageal peristalsis wave (PEP) and upper esophageal sphincter was (40 5±2 9) mmHg and (48 7±18 1) mmHg respectively. They were lower than those in NEHS (45 0±10 5) mmHg and (56 1±21 2) mmHg ( P <0 01). The synchronous esophageal peristalsis waves were found in 13 2% of HE but not found in NEHS. (2)In ERE, the time of LES relaxation was (10 8±1 1)second. It was longer than that in NERE (9 2±3 7) second ( P <0 01). The PEP was (33 2±2 9) mmHg. It was lower than that in NERE (40 3±6 3) mmHg ( P <0 01). Conclusions (1)There were some disturbance of esophageal motility in HE. (2) The disturbances of esophageal motility in ERE were more severe than those in NERE.
出处
《中华老年医学杂志》
CAS
CSCD
北大核心
1999年第1期30-31,共2页
Chinese Journal of Geriatrics
