摘要
通过分析食用富硒粤航一号米作饮食干预的复发性阿弗他溃疡(RAU)患者血清炎性细胞因子的变化,探讨功能稻米对防治RAU的作用。选用以稻米为主食的RAU患者,分试验组1、2,设对照。试验组1食用富硒粤航一号米,试验组2食用市售常规精米,加维生素BCO和维生素E,对照组食用市售常规精米,观察期为6个月。采用放射免疫分析技术,检测治疗前后血清炎性细胞因子TNF-а、IL-2、IL-6、IL-8的变化。试验结果表明,治疗前:试验组1、2两组观察指标对比(P﹥0.05),TNF-а、IL-2与对照相比(P﹤0.01),试验组1、2IL-6、IL-8与对照相比(P﹥0.05)。治疗后:试验组1TNF-а与治疗前相比(P﹤0.01),与对照相比无显著性差异(P﹥0.05)。IL-2与治疗前相比(P﹤0.01),与对照相比(P﹤0.01)。试验组2TNF-а与治疗前相比(P﹤0.01),与对照相比(P﹤0.01)。IL-2与治疗前相比(P﹤0.01),与对照相比(P﹤0.01)。试验组1、2两项相比(P﹤0.01)。表明食用富硒粤航一号米为主食能改善RAU患者的血清炎性细胞因子TNF-а、IL-2的失衡,对防治RAU发病有作用。
The paper analysised the changes of serum cytokine in RAU with Applying yue-hangl rice as diet interfering,and studied the effect of functional rice for prevention and treatment in RAU.40 patients with RAU were selected as the experiment groupl and treated with yue-hangl rice.35 patients with RAU as the experiment group2 were treated with normal milled rice and VitaminBco VitaminE.30 cases in normal check were control group and took normal milled. All cases were determined when the cases took rice before and after six months.The level of serium cytokines, TNF-α,IL-2,6,8 , were determined with radioimmunoassay kits.The results showed that the comparison of before and after treatment of the groupl indicated that TNF-α,IL-2 showed a significant differences （P 〈 0.01）. After treatment, the comparison of the Groupl with group 2 and the control group indicated that TNF-α,IL-2 showed a significant differences （P 〈 0.01）. The comparison of two experiment groups indicated that groupl was better than group2 in the hand of improving serum cytokine.Rich-Se yue-hang 1 rice as main diet could effectively regulate and recover unbalance of serum cytokine TNF-α,IL-2 and was effective for prevention and treatment in patients with RAU.
出处
《广东农业科学》
CAS
CSCD
北大核心
2010年第7期160-162,共3页
Guangdong Agricultural Sciences
基金
广东省科技攻关项目(2006A20202007)
广州医学院科研项目(0703030)
广州市属高校科研项目(08A059)
关键词
复发性阿弗他溃疡
功能米
细胞因子
航天育种
硒
recurrent aphthous ulcer（RAU ）
functional rice
serum cytokine
space breeding
selenium
