摘要
目的探讨胸主动脉粥样硬化与高血压的关系。方法应用多平面经食管超声技术检测４１例正常人、４２例单纯高血压患者和２６例高血压合并心脑血管并发症患者的胸主动脉。结果高血压组与正常组比较，胸主动脉内膜－中层厚度增厚〔（１．３９±０．４６）ｍｍｖｓ（１．１７±０．５０）ｍｍ，Ｐ＜０．０５〕，粥样斑块的发生率明显高于对照组（５０％ｖｓ２．２４％，Ｐ＜０．００１），有心脑血管并发症组内膜－中层厚度增加更为明显〔（１．６９±０．５１）ｍｍｖｓ（１．１７±０．５０）ｍｍ，Ｐ＜０．０１〕，并以复合型斑块为主。心脑血管病变危险因素的多因素Ｌｏｇｉｓｔｉｃ回归分析表明，胸主动脉粥样斑块为主要危险因素。结论①胸主动脉粥样斑块是高血压合并动脉粥样硬化的重要标志，与心脑血管并发症的发生密切相关；②多平面经食管超声技术是检测胸主动脉粥样硬化的可靠方法。
Objective\To
evaluate the relationship between thoracic aortic atherosclerosis and essential
hypertension(EH). Methods\ The thoracic aorta was evaluated by transesophageal
echocardiography (TEE) in 109 patients including control group (n=41), EH group (n=42), EH with
coronary artery disease or with cerebrovascular disease group (EH C, n=26). Results\ The
hypertensive subjects had significantly increased aortic diameter, intimalmedial thickness,
stiffness and decreased aortic distensibility in comparison to control group. The presence of
aortic atherosclerotic plaque and complex plaque were significantly higher in EH C group than
that in EH group (84.62% vs 50%, P<0.01 and 72.72% vs 19.05%, P<0.01). Multiple logistic
regression analysis revealed that aortic plaque was the most important risk factor for coronary
artery and cerebrovascular disease. Conclusions\ ①Aortic atherosclerotic plaque is a marker
of target organ damage in hypertensive patients and an important potential cause of coronary
artery and cerebrovascular disease; ②Hypertension was the important influence factor on
aortic anatomy and function; ③TEE can reliably detect aortic atherosclerotic lesions.
出处
《中华超声影像学杂志》
CSCD
1999年第1期21-23,共3页
Chinese Journal of Ultrasonography
关键词
超声心动图
高血压
胸主动脉
动脉粥样硬化
Echocardiography, transesophageal\ \ Hypertension\ \ Aorta, thoracic\ \
Atherosclerosis
