摘要
目的探讨早期应用盐酸氨溴索对预防和治疗新生儿呼吸窘迫综合征(NRDS)的临床疗效。方法将诊断为NRDS的早产新生儿随机分为对照组和研究组,两组均给予基础对症治疗,研究组在基础治疗的基础上应用盐酸氨溴索治疗,观察两组患儿呼吸窘迫缓解时间、吸氧时间、血气改善情况、胸片变化情况、并发症发生率和病死率等。结果研究组患儿的呼吸窘迫缓解时间、吸氧时间、平均住院时间等均少于对照组,缺氧并发症发生率及病死率明显低于对照组(P<0.05)。结论盐酸氨溴索对预防和治疗NRDS有明显的临床疗效,能够缩短住院时间,降低住院费用,尤其值得基层医院广泛推广。
Objective To investigate the clinical efficacy by early applicationof ambroxol inprevention and treatment of neonatal respiratory distress syndrome（NRDS） . Methods The diagnosis of premature NRDS infants were randomly divided into control group and research group,two groups were given symptomatic treatment,then the research group add ambroxol treatment. To observate the response duration of respiratory distress,oxygen time,improvement of vigor,chest radiograph changes,complications and mortality,etc in tow groups. Results The research group of children with respiratory distress relief time,oxygen time,the average length of time than the control group,hypoxic complication rate and mortality was significantly lower than the control group（P〈0. 05） . Conclusion Ambroxol for prevention and treatment of NRDS have significant clinical effects,and can shorten the length of time,reduce hospitalization expenses,particularly can widely promoted in primary hospitals.
出处
《中国现代药物应用》
2010年第14期6-7,共2页
Chinese Journal of Modern Drug Application
