摘要
目的观察瓣膜病伴心房颤动（房颤）患者血小板的功能以及用β受体阻滞剂治疗的临床意义。方法将确诊为非瓣膜性房颤患者的内皮及血小板功能进行检测,再用β受体阻滞剂对96例患者进行治疗,观察患者血栓栓塞并发症的发生及血小板功能的活化。结果在2周和6周后血浆LPA含量的降低幅度非常显著;治疗的96例患者有效87例,总有效率92.3%,显效71例,显效率73%,无效8例,无效率7.7%,死亡2例,死亡率1.9%。结论β受体阻滞剂治疗方式对患者体内血小板活化有很显著的影响。在常规治疗房颤合并收缩性心力衰竭前提下,用β受体阻滞剂能提高疗效,改善生存率。
Objective To observe the valve disease and atrial fibrillation （AF）, and platelet function in patients with 13 -blocker therapy clinical significance. Methods Patients diagnosed with non-valvular atrial fibrillation endothelial and platelet function testing, and then 13 -blocker treatment in 96 patients, observed in patients with thromboembolic complications and the activation of platelet function. Results in 2 weeks and 6 weeks after the, reduction of plasma LPA.levels increase very significant; treatment of 96 cases were effective in 87 cases, total effective rate of 92.3%, effective in 71 cases, markedly effective rate was 73%, 8 cases, inefficient 7.7%2 patients died, mortality rate 1.9%. Conclusion 13 -blocker therapy on platelet activation has a significant impact. In the conventional treatment of systolic heart failure with atrial fibrillation under the premise of using β-blocker can increase the efficacy and improve survival.
出处
《中国中医药现代远程教育》
2010年第11期231-232,共2页
Chinese Medicine Modern Distance Education of China
