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非对称二甲基精氨酸在动脉粥样硬化发生发展中的作用的研究进展 被引量：1

The role of asymmetric dimethylarginine in development of atherosclerosis
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摘要 非对称二甲基精氨酸（asymmetric dimethylarginine，ADMA）是一种内源性一氧化氮合酶（NOS）竞争性抑制剂，通过抑制NOS减少一氧化氮（NO）合成，导致血管内皮功能紊乱。ADMA是一种血管内皮功能失调的危险因子，也可能是一种前致动脉粥样硬化分子，同时还可能成为心血管疾病新的标志物。ADMA对动脉粥样硬化的作用机制备受众多学者的关注，同时对ADMA的研究也成为现在的研究热点。本文根据最新的研究对ADMA在动脉粥样硬化的发生发展中的作用进行综述。
作者 李丽亚 曾玉杰
机构地区 中日友好医院心内科
出处 《中国心血管病研究》 CAS 2010年第7期534-537,共4页 Chinese Journal of Cardiovascular Research
关键词 非对称二甲基精氨酸 动脉粥样硬化 Asymmetric dimenthylarginine Atherosclerosis
分类号 R541.4 [医药卫生—心血管疾病]
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参考文献32

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二级参考文献19

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中国心血管病研究
2010年 第7期

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