摘要
目的探讨尿毒症患者的医院感染部位分布、相关的危险因素及病原菌分布及耐药情况,以利于有效预防及合理用药,改善预后。方法回顾分析医院2000年1月-2008年12月83例尿毒症患者符合医院感染诊断标准临床资料。结果尿毒症患者医院感染率为10.6%,感染部位依次为呼吸道感染占首位44例(53.0%)、泌尿道21例(25.3%)、胃肠道6例(7.2%)、静脉导管5例(6.0%)、腹膜炎4例(4.8%)、败血症2例(2.4%)、皮肤软组织1例(1.2%);病原菌以革兰阴性菌居多,且耐药率较高。结论尿毒症患者医院感染对抗菌药物耐药情况较明显,临床上应加强病原菌培养及药敏监测,及早正确选用有效抗菌药物治疗,以降低病死率,减少二重感染。
OBJECTIVE To investigate the site of the nosocomial infection,risk factors,and the distribution and drug resistance of bacteria in order to improve prognosis in uremic patients and facilitate the effective prevention and rational use of medicines.METHODS A retrospective analysis of 83 uremic cases with nosocomial infection in our hospital from Jan 2000 to Dec 2008 was conducted.RESULTS The nosocomial infection rate in uremic patients was 10.6%.Among them the respiratory tract infection was the first（44 cases,53.0%）,then the urinary tract infection（21 cases,25.3%）,gastrointestinal tract infection（6 cases,7.2%）,intravenous catheterization infection（5 cases,6.0%）,peritonitis（4 cases,4.8%）,sepsis（2 cases,2.4%）,and skin and soft tissue infection（1 case,1.2%）.Bacteria were predominantly Gram-negatives,and the resistance rate was high.CONCLUSION The antibiotic resistance of nosocomial infection in uremic patients is high.We should strengthen the bacteria cultivation and drug sensitivity monitoring in clinic,choose the correct and effective antibiotic early to reduce mortality and superinfection.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2010年第13期1971-1973,共3页
Chinese Journal of Nosocomiology
关键词
尿毒症
医院感染
病原菌
Uremia
Nosocomial infection
Pathogen
