摘要
目的建立北寒水石的质量标准。方法采用化学鉴别法进行北寒水石的钙盐和硫酸盐的鉴别反应;采用乙二胺四醋酸二钠配位滴定法测定北寒水石中含水硫酸钙(CaSO4.2H2O)的含量。结果乙二胺四醋酸二钠配位滴定法测定北寒水石中含水硫酸钙(CaSO4.2H2O)的含量,重复性好(RSD=0.24%),含水硫酸钙(CaSO4.2H2O)在0.0004～0.2498g线性关系良好(r=0.9997),平均回收率为103.95%,RSD=2.83%(n=6)。6批样品中CaSO4.2H2O的平均含量为98.62%。结论所建立的北寒水石定量测定方法简单准确,能够控制该矿物药的质量。
Objective To establish the method of quality control for Beihanshuishi.Methods To detect calcium salt and sulfate by chemical identification,and to determine the quantity of CaSO4·2H2O in Beihanshuishi by Calcium Disodium Versenate coordination titration Method.Results The method for the determination of CaSO4·2H2O in Beihanshuishi was in good reproducibility（RSD=0.24%）.The calibration curve was linear（r= 0.999 8）within the reage of 0.000 4～0.249 8 g of CaSO4·2H2O.The recovery was 103.95%,RSD=2.83%.Conclusion This method is convenient and accurate,and it can be used to establish quality control of the medicinal material.
出处
《时珍国医国药》
CAS
CSCD
北大核心
2010年第7期1658-1659,共2页
Lishizhen Medicine and Materia Medica Research
基金
国家药典委员会<中国药典>2010年版标准研究课题(YS-198)
关键词
乙二胺四醋酸二钠配位滴定法
北寒水石
Calcium Disodium Versenate coordination titration method,Beihanshuishi
