摘要
目的：通过对足月新生儿缺氧缺血性脑病（ＨＩＥ）的ＭＲＩ分析，找出ＨＩＥ的ＭＲＩ特点。材料和方法：对４５例临床确诊为ＨＩＥ的足月新生儿行ＭＲ检查。采用０．３５Ｔ磁共振仪，选自旋回波序列（ＳＥ），在Ｔ１ＷＩ及Ｔ２ＷＩ上对脑皮层及皮层下白质，深部白质；基底节及丘脑；脑室及蛛网膜下腔等部位进行观察。结果：在Ｔ１ＷＩ上见皮层沿脑回分布点的及条状高信号，深部白质沿侧室壁的条状高信号，基底节及丘脑高信号，幕上及幕下蛛网膜下腔出血呈现的高信号，其发生率分别为８４．４４％，３７．７８％，４２．２２％，１３．３３％与４８．８９％。此外，额叶深部白质内对称的点状高信号也相当特殊，发生率４４．４４％，其它改变有皮层下坏死软化，占２０％，脑室内出血占８．８９％。结论：本文主要描述了足月新生儿ＨＩＥ的ＭＲＩ特点并对其相关的病理基础进行探讨。
Purpose:To identify MRI features of hypoxic-ischemic encephalopathy in full-term neonates.Materials and Methods:Forty-five cases of full-term neonates diagnosed as hypoxic-ischemic encephalopathy(HIE) clinically were examined by 0.35T superconductive MR system.SE T1WI and FSE T2WI sequences.Changes of signal intensities of the lesions in the cortex,subcortical white matter,basal ganglia,thalami,brain stem,periventricular white matter and extra-cerebral regions were observed.Results:On T1WI,streaklike and spotty hyperintensities in the cortex,hperintensities in the areas of basal ganglia and thalami,perivertricular white matter were the most common signs.The incidence of the changes were 84.44%,42.22%,37.78% respectively.The lesions were considered to be neuronal ischemic necrosis in the cortical,subcortical regions,basal ganglia and thalamic areas.Moreover,symmetrical hyperintensities surrounded by edema in the deep white matter of the frontal lobe just in front to the anterior horn were seen in 44.44%.The other features were leukomalasia(11.11%),intraventricular hemorrhage(8.89)on T2WI,the hyperintensities seen on T1WI appeared as hypointensities or isointensities.The MRI features of HIE in full-term neonates were best seen on T1WI.the symmetrical hyperintensities seen in deep frontal white matter represented venous congestion,venous infarct or hemorrhage.Subarachnoid or subdural hemorrhage were often seen near the confluence of the sinuses and subtentorial region.Conclusion:MRI have proven to be a powerful tool in the evaluation of HIE in neonates.
出处
《中国医学计算机成像杂志》
CSCD
1999年第1期47-50,共4页
Chinese Computed Medical Imaging
基金
国家"九五"攻关项目
