摘要
目的:探讨缬沙坦与苯那普利对冠心病合并舒张功能异常患者的临床疗效。方法:将58例冠心病合并舒张功能异常患者随机分成治疗组(30例)和对照组(28例)。两组患者均给予冠心病常规治疗,治疗组加用缬沙坦(代文)80~160 mg/d,对照组加用苯那普利(洛汀新)10~20 mg/d,疗程6个月。疗程结束后,评价患者的临床症状,测定左心室舒张功能指标的改善情况。结果:治疗组总有效率优于对照组(90%比57.1%,P<0.05)。结论:缬沙坦能改善冠心病合并舒张功能异常患者的预后,并能显著改善心脏舒张功能指标。
Objective:To investigate the clinical effect of valsartan and benazepril on the patients with coronary artery disease combined diastolic impaired function.Methods:58 patients with coronary artery disease combined diastolic impaired function were divided into 2 groups:the first group was given valsartan on the basis of the conventional treatment,the another group was given benazepril for control.To compare the clinical curative effects between the two groups.Results:The total effective rate was 90% in the treatment group and 57.1% in the control group with statistical difference(P〈0.05).No severe side effects were observed.Conclusion:The intravenous use of valsartan is safe and effective for coronary artery disease combined diastolic impaired function.
出处
《现代医药卫生》
2010年第14期2100-2101,共2页
Journal of Modern Medicine & Health
关键词
缬沙坦
冠心病
舒张功能异常
Valsartan
Coronary artery disease
Diastolic impaired function