摘要
目的：探讨性激素受体在转移性肝癌中改变的临床意义；方法：用放射配体结合法测定２１例转移性肝癌和２３例原发性肝癌外周血白细胞雌激素受体（ＥＲ）和白细胞雄激素受体（ＡＲ）；结果：转移性肝癌ＥＲ水平明显低于原发性肝癌ＥＲ（Ｐ＜０．０１）。两组ＡＲ水平无显著差异（Ｐ＞０．０５）。两组ＥＲ置信区域基本不重叠；结论：转移性肝癌可能系非激素依赖性肿瘤，ＥＲ６００位点／细胞可作为区分转移性肝癌和原发性肝癌判断标准之一。
Objective To investigated the chang of sex hormonic receptor in metastatic liver cancer and its clinical significance.Method:21 cases with metastatic liver cancer and 23 cases with primary liver cancer(PLC)were detected for serum sex hormonic receptor(ER or AR)by using combined radiolabeled.Results:ER level was very low in patients with metastatic liver cancer than that with PLC.(p<0 05),in which the Confindenced area was no overlapping.AR levels were no significantly different in both group .Conclusion:The metastatic liver cancer dien′t depend on hormonic tumor.ER level (600 positive spots/cells)may be used for a index in differentiating PLC and metastatic liver cancer.
出处
《河北医学》
CAS
1999年第1期32-33,共2页
Hebei Medicine
