摘要
目的：探讨高压氧治疗新生儿缺氧缺血性脑病（HIE）的疗效。方法：将46例中重度HIE患儿中22例按照三维持、三对症原则治疗；24例在常规治疗的基础上采用高压氧协助治疗。2个疗程后，疗效评定。结果：高压氧治疗组显效率54．2％，总有效率83．3％，和常规治疗组结果比较，差异具有显著性（P〈0．05）。结论：HIE发生的根本原因是缺氧，常规治疗基础上早期行高压氧治疗能使迅速缓解症状，译进脑组织损伤后的恢复，减少了后遗症的发生。
Objective： To explore the effect of hyperbaric oxygen treatment in neonatal hypoxic ischemic encephalopathy （HIE）. Methods.. 22 case of 46 patients with moderate to severe HIE patients were treated in accordance with the principle of three maintained and three symptomatic; other 24 cases help with hyperbaric oxygen therapy on the basis of conventional therapy. After 2 courses of treatment, the efficacy was evaluated. Results： In hyperbaric oxygen treatment group, high efficacy rate was 54.2%, and the total effective rate was 83.3% ; compared with conventional treatment group results, the difference was significant （P〈0.05）. Conclusion： Lack of oxygen was the essence reason of HIE, early hyperbaric oxygen treatment on the onventional therapy could quickly relieve symptoms, promote recovery after brain injury, and reduced the incidence of complications.
关键词
新生儿
缺氧缺血性脑病
高压氧
后遗症
Newborn
hypoxic ischemic encephalopathy
hyperbaric oxygen
sequelae
