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N-(末端三甲基硅苄基甘氨酸肽链)邻苯二甲酰亚胺的光诱导单电子转移成环反应 被引量：6

Photoinduced Single Electron Transfer Cyclization Reactions of N-(Amidosilane terminated polybenzylglycine peptide chain)phthalimide
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摘要 以苄基甘氨酸为起始原料合成N-(末端三甲基硅苄基甘氨酸肽链)邻苯二甲酰亚胺(1).1在甲醇溶剂中光照发生单电子转移反应,生成分子内双自由基10,自由基偶合生成环聚甘氨酸肽化合物2.此反应产率好,区域选择性高.所有新化合物结构均经NMR和质谱验证. Benzylglycine was used as starting material for the synthesis of N-（amidosilane teminated polybenzylglycine peptide chain）phthalimide（1）.Irradiating methanol solution containing 1 is observed to promote formation of biradical 10.Then the biradical 10 copulates to give cyclopolyglypeptides 2 in high yield and high selectivity.The structures of all the new compounds were characterized by MS and NMR techniques.
作者 金英学 谭广慧 赵俊明 张鹏 王丙南 郑鹏
机构地区 哈尔滨师范大学化学化工学院
出处 《有机化学》 SCIE CAS CSCD 北大核心 2010年第6期860-864,共5页 Chinese Journal of Organic Chemistry
基金 国家自然科学基金(No.20972036) 黑龙江省教育厅海外学人科研基金(No.1152hq23) 国家人事部留学人员科技活动择优(No.[2007]275)资助项目
关键词 光诱导 单电子转移 环肽化合物 合成 photoinduced single electro transfer cyclic peptide compound synthesis
分类号 O621.25 [理学—有机化学]
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同被引文献25

  • 1窦辉,廖循,陈昌祥,彭树林,周燕,丁立生.四齿四棱草根部环肽化合物的分离及鉴定[J].高等学校化学学报,2004,25(10):1849-1852. 被引量：11
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有机化学
2010年 第6期

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