摘要
目的探讨胚胎发育中胎龄及胚体大小与胰岛细胞分化的相关性。方法收集妊娠6～14周的胚胎20例,测其重量,顶臀径并通过免疫组织化学染色观察胰高血糖素(glucagon)在胰岛细胞分化过程中的表达。结果妊娠9周左右,胚体重约2.89±0.12g,顶臀径约30.0±2.8mm,此时胰腺导管上皮细胞开始分化出胰岛细胞,并且具有内分泌功能。结论妊娠发育的胚胎在胎龄9w、顶臀径30mm、重量约为2.89g左右时,胰岛细胞开始从胰腺导管上皮细胞分化。
Objective To investigate the relationship between embryonic gestation, embryonic body size and islet cells differentiation in embryonic development. Methods 20 samples collection was conducted in accordance to the principle of informed consent. The weight, parietal-buttocks diameter were measured and the histochemicaI SABC method was adopted for studying Glugagon expression in islet cells of the developing embryo. Results About 9 weeks pregnancy, embryonic body weight was 2.89±0. 12 g, parietal-buttocks diameter being 30.0±2.8 mm ap- proximately, and the pancreatic duct epithelial cells were seen to being differentiate to islet cells with endocrine function. Conclusion The development embryo at 9 weeks gestation, with parietal-buttocks diameter 30 mm and the weight being about 2.89 g, the islet cells begin to differentiate from the pancreatic duct epithelial cells.
出处
《四川解剖学杂志》
2010年第2期4-6,共3页
Sichuan Journal of Anatomy
基金
大学生基金(2008DX5026)
