期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

高同型半胱氨酸血症与脑梗死的关系 被引量：5

暂未订购
导出
摘要 目的:探讨脑梗死发病和病情程度与高同型半胱氨酸(Hcy)血症及叶酸、维生素B12缺乏的相关性。方法:检测136例急性脑梗死病人和70例对照组Hcy及血浆叶酸、维生素B12水平。结果:急性脑梗死组血浆Hcy高于对照组(P<0.01)。轻、中、重型脑梗死组的血浆Hcy表现为逐渐对应升高(P<0.05)。部分脑梗死合并高Hcy血症的患者接受了维生素B12、叶酸治疗后,血浆Hcy水平显著下降(P<0.01)。结论:高Hcy血症与急性脑梗死的发病存在相关性,血浆Hcy水平可以作为急性缺血性脑卒中的检查及诊治观察的实验室指标。
作者 欧阳强 韦英海 陈阳
机构地区 广西壮族自治区民族医院神经内科
出处 《广西医科大学学报》 CAS 2010年第3期433-434,共2页 Journal of Guangxi Medical University
关键词 急性脑梗死 高同型半胱氨酸血症 叶酸 维生素B 12
分类号 R743 [医药卫生—神经病学与精神病学]
  • 相关文献

参考文献7

二级参考文献21

  • 1Tsai MY,Welge BG,Hanson NQ,et al.Genetic cause of mile hyperhomocysteinemia in patients with premature occlusive coronary artery diseases[J].Atherosclerosis,1999,143:163.
  • 2McCully KS.Vascular pathology of homocysteinemia: implication for the pathogenesis of arteriosclerosis[J].Am J Pathol,1969,56: 111.
  • 3Perry IJ,Refsum H,Morris PW,et al.Prospective study of serum total homocysteine concentration and risk of stroke in middle-aged British men[J].Lancet,1995,346:1395.
  • 4Yoo JH,Chung CS,Kang SS.Relation of plasma homocysteine to cerebral infarction and cerebral atherosclerosis[J].Stroke,1998,29:2478.
  • 5Stchouwur DA,Weijenberg PM,Den Berg V,et al.Serum homocysteine and risk of coronary heart disease and cerebrovascular disease in elderly men,a 10-year-follow-up[J].Arterioscler Thromb Vasc Biol,1998,18:1895.
  • 6Gerritsent T,Vaughn JG,Waisman HA.The identification of homocystine in the urine.Biochem Biophys Res Commun,1962,9:493
  • 7Carson NAJ,Neill DW.Metabolic abnormalities detected in a survey of mentally backward individuals in Northern Ireland.Arch Dis Child,1962,37:505
  • 8McCully KS.Vascular pathology of homocysteinemia:implications for the pathogenesis of arteriosclerosis.Am J Pathol,1969,56:111
  • 9McCully KS.Atherosclerosis,serum cholesterol and the homocysteine theory:A study of 194 consecutive autopsies.Am J Med Sci,1990,299:217
  • 10Clarke R,Daly l,Robinson K,et al.Hyperhomocysteinemia:an independent risk factor for vascular disease.N Engl J lied,1991,324:1149

共引文献33140

同被引文献27

  • 1范红燕,吴素慧.同型半胱氨酸在绝经期妇女冠心病预防中的作用[J].山西医科大学学报,2005,36(2):241-243. 被引量：8
  • 2各类脑血管疾病诊断要点[J].中华神经科杂志,1996,29(6):379-380. 被引量：33093
  • 3Herrmann W. The importance of hyperhomocysteinemia as a risk factor for diseases: an overviw[J] . Clin Chem Lab Med, 2001,39(8):666-674.
  • 4Tanne D,Haim M,Goldbourt U,et al. Prospective study of se-ronl homocysteine and risk of ischemic stroke among patients with preex-isting coronary heart disease[J] . Stroke,2003,34 ￠3):632-636.
  • 5Lippi G,Plebani M. Hyperhomocysteinemia in health and disease: where we are now,and where do we go from here?[J]. Clin Chem Lab Med, 2012,50 (12) : 2075-2080.
  • 6Herrmann W,Obeid R. Homocysteine :A biomarker in neu- rodegenerative diseases[J]. Clin Chem Lab Med,2011,49 (3) :435-441.
  • 7Lim U, Cassano PA. Homocysteine and blood pressure in the 3rd National Health and Nutrition Examination Sur- vey, 1988-1994[J]. Am J Epidemiol,2002,156(12) : 1105- 1113.
  • 8Ma YY,Shek CC,Wong MC,et al. Homocysteine level in schizophrenia patients[J]. Aust N Z J Psychiatry,2009,43 (8) :760-765.
  • 9Kim TH,Moon SW. Serum homocysteine and folate levels in korean schizophrenic patients[J]. Psychiatry Investig, 2011,8 (2) : 134-140.
  • 10Scott JM,Weir DG. Folic acid,homocysteine,and one-car- bon metabolism:A review of the essential biochemistry[J]. J Cardiovasc Risk, 1998,5(4) :223-227.

引证文献5

二级引证文献23

广西医科大学学报
2010年 第3期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部