摘要
目的:通过分析影响持续非卧床腹膜透析(CAPD)患者发生腹膜炎的因素,为腹膜炎的防治制定合理的方案。方法:调查2005年2月1日～2009年10月31日行CAPD患者的临床资料,以单因素方差分析及COX回归法分析影响患者发生腹膜炎的因素。结果:105例患者中有35例发生53次腹膜炎。致病菌中革兰阳性菌多见。术后1月内培养出的致病菌均是球菌类,而术后1月后杆菌类占43.5%。在导致腹膜炎的原因中,操作因素及消化道因素占67.9%。糖尿病患者腹膜炎发生率为36.8%,非糖尿病患者腹膜炎发生率为32.6%。白蛋白浓度下降与患者发生腹膜炎相关(P<0.01)。结论:腹膜透析相关性腹膜炎最常见的细菌仍是球菌类。术后早期发生的腹膜炎均是球菌类,可能与早期操作不熟练相关;术后1月后杆菌类比例迅速增加,可能为消化道因素增多所致。相对于非糖尿病患者,糖尿病腹膜透析患者腹膜炎的发生率高,无腹膜炎生存时间短。白蛋白浓度降低为腹膜炎发生的高危因素。
Objective：To analyze the clinical characteristics that influence the risk of dialysis-related peritonitis complication.Methods：A retrospective method was used to anlyyze the risk factors of dialysis-related peritonitis.Results：Between Feb.2005 and Oct.2009,105 CAPD patients were recruited for analysis.During the study period,53 episodes of peritonitis were recorded.The most common mircrorganism in early postoperative（〈1 months） dialysis-related peritonitis was coccobacteria,and gram-negative bacilli was popular（43.5%） in late postoperative dialysis-related peritonitis.According to multivariate Cox proportional hazards model,low serum albumin concentration was associated with peritonitis.Conclusion：The early postoperative dialysis-related peritonitis may be associated with exchange practices.The disorder of bowel may predispose the late postoperative dialysis-related peritonitis.Our results confirm the susceptibility of hypoalbuminemic patients to peritonitis,and highlight the role of further studies in reducing this complication.
出处
《中国中西医结合肾病杂志》
2010年第3期219-221,共3页
Chinese Journal of Integrated Traditional and Western Nephrology
关键词
腹膜透析
腹膜炎
糖尿病
Peritoneal dialysis Peritonitis Diabetes mellitus
