摘要
为了探讨肝包虫病患者血清白细胞介素6（IL－6）和肿瘤坏死因子a（TNF－a）水平及其与肝包虫病的关系，应用ELISA法检查42例正常人、27例肝包虫病人血清TNF－a水平，其中20例病人同时检测IL－6水平，结果显示肝包虫病患者血清IL－67水平为0．1626±0．100ng／ml，显著高于正常人0．0191±0．0168ng／ml（P＜0．001），TNF－a水平为8．9946±5．3112ng／ml，也显著高于正常人2．2967±0．9317ng／ml（P＜0．01），作者认为对IL－6和TNF－a水平的检测可作为肝包虫病患者免疫功能检查指标之一，对肝包虫病的发病机制并对疾病的严重程度、疗效及预后的判断具有重要意义。
The relation between the level of IL-6, TNF-a and hepatic hydatidosis were detected in 27 cases of hepatic hydatidosis and 42 cases of healthy individuals by ELISA.The result showed that the levels of serum IL-6 and INF-a in cases of hepatic hydatidosis were 0. 162 610. 100 6 ng/ml and 8. 994 6± 5. 311 2 ng/ml which were significantly higher than those of control group (0. 019 ± 0. 016 8ng/ml and 2. 296 7+0.931 7ng/ml) (P<0. 001 ).This article suggested that the detection of IL-6 and TNF-a act as an important index for the diagnosis, treatment and prognosis of patients with hepatic hydotidosis.
出处
《地方病通报》
1999年第1期10-12,共3页
Endemic Diseases Bulletin
