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原发性甲状旁腺功能亢进症14例误诊分析 被引量:6

Analysis of misdiagnosis of 14 cases of primary hyperparathyroidism
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摘要 目的探讨原发性甲状旁腺功能亢进症(PHPT)的临床特点、误诊原因,寻求降低误诊率的有效措施。方法对1998年1月~2007年12月福州总医院收治的14例PHPT患者的主要临床表现、实验室检验及影像学检查结果等资料进行回顾性分析。结果 l4例PHPT患者,13例接受手术治疗,术后病理明确诊断者中,7例为甲状旁腺腺瘤,5例为甲状旁腺增生,1例为甲状旁腺腺癌;误诊病种达10余种,38例次,主要为各种类型关节炎,泌尿系结石,多发骨髓瘤等。14例患者误诊率高达85.71%。结论应提高对PHPT的认识,对疑诊者早期检测血钙和甲状旁腺激素,行颈部B超和CT等影像学检查定位诊断,减少PHPT的误诊率。 Objective To investigate clinical features of primary hyperparathyroidism and to explore the causes of misdiagnose in order to find effective measures to reduce the misdiagnosis rate.Methods Fourteen cases of primary hyperparathyroidism admitted to Fuzhou General Hospital from January 1998 to December 2007 were analyzed retrospectively,including their main clini cal manifestations and results of laboratory and imaging examination.Results Seven cases were confirmed as parathyroid adenoma,5 cases hyperplasia and 1 case carcinoma by pathological examinations.The fouteen cases were misdiagnosed as 10 sorts of diseases,mainly including various type of arthritis(71.4%),urinary stones(35.71%)and pathologic fracture(35.71%),misdiagnosis rate as high as 85.71%.Conclusions The awareness of PHPT should be raised.For suspected patients,serum calcium and serum PTH measurement,neck ultrasound and CT imaging ought to be applied at early stage to reduce the misdiagnosis rate of PHPT.
出处 《中华保健医学杂志》 2010年第3期195-197,共3页 Chinese Journal of Health Care and Medicine
关键词 原发性甲状旁腺功能亢进症 误诊 诊断 Primary hyperparathyroidism Misdiagnosis Diagnosis
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