期刊文献+

苏子油软胶囊对30例2型糖尿病患者血糖、血脂的影响 被引量:5

暂未订购
导出
摘要 目的观察苏子油软胶囊治疗2型糖尿病的临床疗效。方法 60例2型糖尿病患者随机分为治疗组和对照组各30例,治疗组服用盐酸二甲双胍加苏子油软胶囊,对照组单纯服用盐酸二甲双胍。2组疗程均为60d,治疗前后分别检测空腹血糖(FBG)、餐后血糖(P2hBG)、空腹胰岛素(Fins)、糖基化血红蛋白(HBA1c)、血脂,计算胰岛素抵抗指数(HOMA-IR)等。结果 2组治疗前后比较各项检测指标均有显著改善(P<0.01),组间比较,治疗组检测指标改善更为明显(P<0.05)。结论苏子油软胶囊治疗T2DM有确切的临床疗效,而且能明显改善患者的HOMA-IR,降低胰岛素抵抗。
作者 何煜峰
机构地区 邵武市中医院
出处 《福建中医药》 2010年第3期15-16,共2页 Fujian Journal of Traditional Chinese Medicine
  • 相关文献

参考文献10

  • 1钱立荣.糖尿病临床指南[M].北京:北京医科大学出版社,2000:214.
  • 2HAFFNER S M,KENNEDY E,GONZALEZ C,et al.A prospective analysis of the HOM A model:the mexica city diabetes study[J].Diabetes Care,1996,19(10):1138-1141.
  • 3HAFFNER S M,MIETTLNEN H,STERN M P.The homeostxsis-model in the San Autonio heart study[J].Diabetes Care,1997,20(7):1087.
  • 4唐迎雪.2型糖尿病胰岛素抵抗与中医痰瘀毒相关性研究[J].中国医药学报,2004,19(4):237-239. 被引量:28
  • 5MCGARRY J D.Dysregulation of fatty acid metabolism in the etiology of type 2 diabetes[J].Diabetes,2001,50(suppl 2):6.
  • 6王宏钊,缪珊,孙纪元.α-亚麻酸药理研究进展[J].国际药学研究杂志,2007,34(4):254-258. 被引量:32
  • 7陈银基,周光宏,徐幸莲.n-3多不饱和脂肪酸对疾病的预防与治疗作用[J].中国油脂,2006,31(9):31-34. 被引量:31
  • 8毛童俊,陈伟平.n-3多不饱和脂肪酸治疗糖尿病的分子机制研究进展[J].国外医学(卫生学分册),2008,35(6):352-355. 被引量:3
  • 9DECSI T,MINDA H,HERMANN R,et al.Polyunsaturated fatty ecids in plasma and erythrocyte membrane lipids of diabetic children[J].Prostagtandins Leukot Essent Fatty Acids,2002,67(4):203-210.
  • 10GHAFOORUNISSA,IBRAHIM A? NATARAJAN S.Substituting dietary linolenic acid with alpha-linolenic acid improves insulin sensitivity in sucrose fed rats[J].Biochim Biophys Acta,2005,1733 (l):67-75.

二级参考文献89

  • 1刘艳骄,王琦.肥胖人痰湿体质与糖尿病相关性研究[J].山东中医学院学报,1993,17(2):34-39. 被引量:77
  • 2陶辉宇,李丽,陈杰斌,谭小进,李双杰.纳米α-亚麻酸对大鼠阿霉素心肌损伤的保护作用及其抗氧化机制研究[J].中国现代医学杂志,2006,16(13):1978-1982. 被引量:8
  • 3NETTLETON J A, KATZ R. n-3 Long-chain polyunsaturated fatty acids in type 2 diabetes: a review [ J ]. Am Diet Assoc,2005,105(3) :428-440.
  • 4JUMP D B, BOTOLIN D, WANG Y, et al. Fatty acid regulation of hepatic gene transcription [ J ]. Nutr, 2005,135 ( 11 ) :2503-2506.
  • 5FERRE P. The biology of peroxisome proliferator-activated receptors: relationship with lipid metabolism and insulin sensitivity[J]. Diabetes, 2004,53 : 43-50.
  • 6MOTOJIMA K, PASSILLY P, PETERS J M, et al. Expression of putative fatty acid transporter genes are regulated by peroxisome proliferators-activated receptor alpha and gamma activators in a tissue and inducer-specific manner[J]. Biol Chem, 1998,273(27) : 16710-16714.
  • 7GULICK T, CRESCI S, CAIRA T, et al. The peroxisome proliferators-activated receptor regulates mitochondrial fatty acid oxidative enzyme gene expression [ J ]. Proc Natl Acad Sci,1994,91:11012-11016
  • 8MUOIO D M,WAY J M, TANNER C J, et al. Peroxisome proliferators-activated receptor alpha regulated fatty acid utilization in primary human skeletal muscle cells [ J ]. Diabetes, 2002,51 : 901-909.
  • 9LUQUET S,GAUDEL C, HOLST D, et al. Roles of PPAR delta in lipid absorption and metabolism:a new target for the treatment of type 2 diabetes [ J ]. Biochimica Biophysica Acta,2005,1740(2) :313-317.
  • 10OLIVERWR, SHENK J L, SNAITH M R, et al. A selective peroxisome proliferator-activated receptor δ agonist promotes reverse cholesterol transport [ J]. Proc Natl Acad Sci,2001,98(9) :5306-5311.

共引文献99

同被引文献100

引证文献5

二级引证文献57

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部