摘要
目的分析学龄儿童日本血吸虫感染率与社区人群感染率之间的相关关系。方法通过检索CNKI和PubMed,收集1990-2009年公开发表的在中国大陆开展的有关年龄分层日本血吸虫感染率的相关文献,采取最小二乘法和极大似然法,以线性回归和logistic回归对学龄儿童与社区总人群、学龄儿童与社区中其他人群日本血吸虫感染率之间的关系进行拟合分析,以期找到最适的回归拟合。结果变换后的logistic回归拟合学龄儿童与社区人群日本血吸虫感染率之间关系的效果最好,回归系数aG、bG、aI、bI、aA、bA值分别为0.4718、6.8462、0.7985、9.6128、0.1619和4.2688。结论学龄儿童日本血吸虫感染率可考虑作为评估中国社区人群日本血吸虫感染率的一个指标。
Objective To investigate the relationship between the prevalence of Schistosoma japonicum infection in school-aged children and that in the general population of the community.Methods The age-stratified infection data of S.japonicum infection in China,which were published in CNKI and PubMed were retrieved from 1990 to 2009.The data of the prevalence of infection in entire population,infants,adults and school-aged children were fitted by using the linear and logistic regression models that took into account of variation in sample prevalences.Results Despite the wide variations in the study sites and date of the survey,a remarkably consistent pattern emerged in the relationship between the prevalence of infection in school-aged children and the prevalence in the community.Conclusion The prevalence of infection in school-aged children could provide a cost-effective predictive tool that can be used at a district/national level to identify target areas for control and to evaluate the numbers at risk of infection in China.
出处
《中国血吸虫病防治杂志》
CAS
CSCD
北大核心
2010年第3期221-227,共7页
Chinese Journal of Schistosomiasis Control
基金
国家自然科学基金(30671836)
关键词
日本血吸虫病
感染率
指标
学龄儿童
社区
中国
Schistosomiasis japonica
Prevalence
Indicator
School-aged children
Community
China