摘要
维生素Ｃ和连二亚硫酸钠混合后只能加速猪脾铁蛋白释放铁的速率，并不能使铁蛋白释放铁的动力学途径由复杂转化为简单．而单独维生素Ｃ却能利用蛋白壳上的电子隧道传递电子，迫使铁蛋白以二分之一的反应级数方式释放整体铁核的铁并起着抗磷酸盐阻遏释放铁速率的作用，简化释放铁的途径．对维生素Ｃ参与铁蛋白释放铁的机理进行了讨论．
Rate of iron release from horse spleen ferritin was only accelerated by mixing both vitamin C and dithionite,which could hardly transfer kinetic pathway that the ferritin released iron could from complexity to simplicity.However,vitamin C alone was able to utilize the electrons tunnel on the protein shell for transferring electron to make the ferritin release the iron of whole core as a form of half order reaction,playing a role in resisting the effect phosphate on inhibition rate of iron release,and simplifying the pathway of iron release.The mechanism involving in the process of ferritin releasing iron with the vitamin C reduction was suggested.
出处
《中国生物化学与分子生物学报》
CAS
CSCD
1999年第1期10-14,共5页
Chinese Journal of Biochemistry and Molecular Biology
基金
国家自然科学基金
国家教育部留学回国人员基金
关键词
猪脾铁蛋白
电子隧道
动力学
蛋白壳调节作用
Pig spleen ferritin,Electron tunnel,Kinetics,Regulation action of protein shell
