摘要
目的:了解我院药品不良反应(ADR)发生的特点及一般规律。方法:对我院2008年1月1日～2009年12月31日临床各科室上报的ADR病例,按照国家ADR监测中心制定的标准进行归类、分析。结果:114例ADR监测报告中,涉及药品52种,由抗菌药物引起的疑似ADR最为常见,共47例(占41.2%),由循环系统用药引起的疑似ADR其次,有28例(占24.6%);再者是由抗肿瘤药引起的疑似ADR,有9例(占7.9%);发生率最高的给药途径是静脉给药(85.1%);ADR的临床表现以皮肤及其附件损害最为多见,有57例(占41.61%)。结论:临床应重视ADR的报告和监测,以减少或避免ADR的发生,保障患者用药安全。
OBJECTIVE:To probe into the characteristics and regularity of the adverse drug reactions(ADRs) occurred in our hospital.METHODS:The ADR cases reported by clinical departments from Jan.1,2008 to Dec.31,2009 were classified and analyzed in accordance with the standard set by StateADRMonitoringCenter.RESULTS:52 kinds of drugs were involved in the total 114 ADR cases monitored,leading the list were antibiotics which caused 47(41.2%) suspected ADR cases,followed by circulatory system drugs with 28 suspected ADR cases(24.6%) and anticancer drugs with 9(7.9%).85.1% of the ADR cases were induced intravenously.Lesions of skin and its appendence were the most common clinical manifestations of ADR [57 cases(41.61%)].CONCLUSION:Importance should be attached to the reporting and monitoring of ADR so as to lessen or avoid the occurrence of ADR and ensure patients medication safety.
出处
《中国医院用药评价与分析》
2010年第6期570-572,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
药品不良反应
报告
分析
Adverse drug reactions
Report
Analysis
