摘要
目的:评价地塞米松与布地奈德短期雾化吸入治疗毛细支气管炎的临床疗效。方法:将120例毛细支气管炎患儿随机分成地塞米松组60例和布地奈德组60例,在常规治疗的基础上,分别采用氧气驱动雾化吸入地塞米松(国产)和布地奈德(进口),观察两组患儿的烦躁、喘憋、心率恢复正常、肺部啰音消失时间及平均住院天数等情况,并对其疗效进行对比?峁毫阶榛级挠行史直鹞?93%、92%,差异无统计学意义(P>0.05);两组患儿的烦躁、喘憋、心率恢复正常、肺部啰音消失时间及平均住院天数分别为1.62±0.75、2.63±0.66、6.83±1.46、6.27±1.23、8.2±1.22和1.53±0.68、2.72±0.72、6.69±0.69、6.25±1.37、8.0±1.35,差异亦无统计学意义(P>0.05)。结论:短期雾化吸入地塞米松治疗小儿毛细支气管炎不但安全、有效,而且更加经济,适合基层医院患儿使用。
OBJECTIVE：To evaluate the efficacy of dexamethasone versus short term budesonide inhalation for capillary bronchitis.METHODS：A total of 120 cases of infants with capillary bronchiolitis were randomly assigned to receive either domestic dexamethasone（n =60） or imported budesonide（n =60） in addition to routine therapy for all patients.The recovery time of patients irritability-restlessness,dyspnea and heart rates,the time for disappearance of rales,and average hospital days as well as the curative efficacy in two groups were followed and compared.RESULTS：There were no statistically significant differences between the two groups in effective rate（93% vs.92%,P 0.05）.The recovery time of patients irritability-restlessness,dyspnea,abnormal heart rates,the time for disappearance of rales,and the average hospital days were not statistically significant between two groups（1.62 ±0.75,2.63 ±0.66,6.83 ±1.46,6.27 ±1.23,and 8.2 ±1.22,respectively versus 1.53 ± 0.68,2.72 ± 0.72,6.69 ± 0.69,6.25 ± 1.37,and 8.0 ± 1.35,respectively,P 0.05）.CONCLUSION：Treatment of capillary bronchitis in children with short-term inhalation of dexamethasone is safe,effective and economical,thus applicable for patients in primary hospital.
出处
《中国医院用药评价与分析》
2010年第6期534-535,共2页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
毛细支气管炎
糖皮质激素
雾化吸入
疗效分析
Capillary bronchiolitis
Glucocorticosteroid
Inhalation
Curative efficacy analysis
