摘要
目的观察肠上皮间淋巴细胞与慢性末端回肠炎的关系。方法经结肠内镜及病理学确诊,收集部位相同的慢性末端回肠炎组织共49例,男34例,女15例,平均年龄33.0岁,其中轻度17例,中度16例,重度16例。正常对照组10例,男5例,女5例,平均年龄34.5岁。分别对两组肠上皮间淋巴细胞计数和末端回肠的炎症浸润程度分级并进行对比分析。结果①临床症状的轻重与内镜、病理学下炎症程度无明显相关。②肠上皮间淋巴细胞的计数与内镜下慢性末端回肠炎的炎症程度成正相关(P<0.01)。③肠上皮间淋巴细胞计数与病理学炎性细胞浸润程度成正相关(P<0.01)。结论肠上皮间淋巴细胞可能在慢性末端回肠炎发病及致病过程中发挥重要作用。
Objective To explore the relation between intestinal intraepithelial lymphocyte and chronic terminal ileitis.Methods Forty-nine patients,including 34 males and 15 females with an average age of 33.0,were studied.They had chronic terminal ileitis at the same location,including mild degree of ileitis in 17,moderate degree in 16 and severe degree in 16,which were proved by enteroscopy and pathologic diagnosis.Control group contained 10 patients,5 males and 5 females,with an average age of 34.5.The number of intestinal intraepithelial lymphocytes was counted,the degree of inflammation was classified,and the results were compared and analysed in the two groups.Results ① The clinical symptoms had no obvious relationship with the inflammation degree observed under endoscope.② The number of intestinal intraepithelial lymphocytes was positively related to the degree of inflammation observed under endoscope in chronic terminal ileitis （P0.01）.③ The number of intestinal intraepithelial lymphocytes was positively related to the infiltration degree of the pathological inflammatory cells （P0.01）.Conclusion Intestinal intraepithelial lymphocytes might play an important role in the development and progression of chronic terminal ileitis.
出处
《华南国防医学杂志》
CAS
2010年第3期205-207,共3页
Military Medical Journal of South China
关键词
慢性末端回肠炎
内镜
肠上皮间淋巴细胞
Chronic terminal ileitis
Endoscope
Intestinal intraepithelial lymphocytes
