摘要
目的通过分析中国大陆近30年血吸虫病对人体泌尿生殖系统损害的病例资料,为诊断、治疗和防控非主要寄生部位的血吸虫病提供较系统的数据支持。方法收集、整理大陆1980-01/2009-12多种寄生虫学科技期刊、专著、临床医学杂志、医学书籍等有关我国不同地区的人体血吸病资料,分析发病原因与危害状况。结果大陆近30年报道的血吸虫病对人体泌尿生殖系统损害的病例为169例,分布于四川、云南、湖南、湖北、福建、江西、安徽、江苏、浙江、陕西10省。除福建21例与陕西1例系援外工程人员在国外感染埃及血吸虫回国后发病外,其余147例均来自国内南方日本血吸虫病流行区。患者最小年龄为6岁,最大68岁,男性122人,女性47人,男性患者为女性的2.6倍。患者职业为农民、工人、儿童、学生、教师。3-12月均有发病,患者潜伏期3d2年不等。169例患者中有149例表现为肾脏损害,2例膀胱损害,2例精索、鞘膜、睾丸、副睾的损害,11例卵巢损害,3例子宫损害,2例输卵管损害。吡喹酮治愈率为98.73%,福阿亭治愈率为66.67%,显效率为33.33%,硝硫氰胺治愈率为100%。结论重视人群健康教育,加强粪便无害化管理,提高基层医务人员对该病的诊治水平,注意对来自于疫区患者的病史问诊与实验室检查,不仅是控制血吸虫病流行与传播的有效措施之一,也是防止该病在非常见部位危害人体健康的主要手段。
Objectives To analyze the data of schistosomiasis-caused urogenital system damage cases in mainland of China in recent 3 decades and provide evidence for the diagnosis,treatment and prevention of the damage in uncommon parasitizing sites of Schistosoma.Methods The data about human schistosomiasis cases were reviewed,which were collected from varieties of literatures in parasitological journals/monographs,clinical medical journals and medical books in mainland of China from January 1980 to December 2009,to understand the distribution,etiology and damage status of these cases.Results A total of 169 cases of schistosomiasis-caused urogenital system damage were reported during this period.The cases were distributed in 10 provinces（Sichuan,Yunnan,Hunan,Hubei,Fujian,Jiangxi,Anhui,Jiangsu,Zhejiang and Shaanxi）.Most cases were reported in Jiangxi and Fujian.Except 21 cases in Fujian and 1 case in Shaanxi which were infected with schistosoma hematobium abroad,the others（147）were infected with Schisotosoma japonicum in endemic areas in southern China.The youngest case was 6 years old and the oldest one was 68 years old.The male case number was 122 and female case number was 47,the case number in males was 2.6 times higher than that in females.The population affected included farmers,workers,children,students and teachers.The infection mainly occurred from March to December of a year,the incubation period ranged from 3 days to 2 years.The disease caused a variety of damages of human urogenital system,including 149 damages of kidney,2 damages of bladder,2 multiple damages of spermatic cord,tunica vaginalis,testis and epididymis,11 damage of ovaries,3 damage of uterus and 2 damages of ovarian duct.The cure rate by praziquantel was 98.73%,the cure rate was 66.67% and the effective rate was 33.33% by fuadin and the cure rate by nithiocyanamine was 100%.Conclusion Emphasis of mass health education,harzard-free treatment of human and animal excrement,improving diagnosis and treatment abilities of local medical staff,paying attention to inquiry of disease history and timely laboratory examination could play important role not only in blocking schistosomiasis transmission but also in the control and prevention of schistosomiasis-caused damages in uncommon parasitizing sites of human body.
出处
《寄生虫病与感染性疾病》
CAS
2010年第2期62-67,共6页
Parasitoses and Infectious Diseases
关键词
中国大陆
血吸虫病
泌尿生殖系统
损害
Mainland of China
Schistosomiasis
Urogenital system
Damage
