摘要
目的探讨高龄患者施行肾移植术的特点。方法对31例年龄超过50岁的肾移植患者的资料进行回顾性分析,其中年龄最大者72岁。结果31例患者,存活25例,死亡6例,其中4例于术后近期死亡,2例死于肺部感染,1例死于脑血管意外,1例死于骨髓抑制,另2例分别于术后18个月、2年死于肝癌和猝死。术后发生超急性排斥1例,急性排斥7例次,肺部感染7例,尿路感染5例。结论高龄并非肾移植的绝对禁忌证;高龄患者耐受力差,常伴随其它疾病,术前准备、术中麻醉及监测、术后并发症的防治、免疫抑制剂毒副作用的监测尤为重要;术后并发症,尤其是肺部感染是高龄患者的主要死亡原因。
Objective To investigate the kidney transplantation for 31 advance age patients. Methods From May 1992 to Dec. 1997, 31 patients over 50 years old received the cadaver kidney transplantation, and the data were retrospectively analyzed. Results The survival rate of person/kidney one year after transplantation was 87.1 %/ 81.2% , respectively. The common complications of advanced age patients after kidney transplantation included lung infection, cerebrovascular accident and myocardial infarction, etc.. Conclusion Advance age was not the absolute contraindication for kidney transplantation. It is particular important to conduct preoperative preparation, perioperative anesthesia and monitoring, the prevention and treatment of the postoperative complications, and the monitoring of the toxic and side effects of immunosuppressive agent, etc.. The postoperative complications, especially lung infection, are the main dead factors for advanced age CRF patients receiving kidney transplantation.
出处
《中华器官移植杂志》
CAS
CSCD
1999年第1期43-44,共2页
Chinese Journal of Organ Transplantation
关键词
老年人
肾移植
移植物生存
Aged Kidney/transplantation Graft survival