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Toll样受体及其通路是中医药干预艾滋病免疫重建的可能作用靶点 被引量:14

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作者 汤艳莉 王阶
出处 《中国中西医结合杂志》 CAS CSCD 北大核心 2010年第6期665-668,共4页 Chinese Journal of Integrated Traditional and Western Medicine
基金 国家科技重大专项资金资助课题(No.2008ZX10005-004)
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参考文献31

  • 1Medzhitov R,Preston-Hurlburt P,Janeway CA Jr.A human homologue of the drosophila toll protein signals activation of adaptive immunity[J].Nature,1997,388 (6640):394-397.
  • 2Takeda K,Kaisho T,Akira S,et al.Toll-like receptors[J].Annu Rev Immunol,2003,21:335-376.
  • 3Heil F,Ahmad-Nejad P,Hemmi H,et al.The Toll-like receptor 7(TLR7)-specific stimulus loxoribine uncovers a strong relationship within the TLR7,8 and9 subfamily[J].EurJ Immunol,2003,33(11):2987-2997.
  • 4张群,雷林生,吴曙光.多糖类药物作用的受体及信号转导机制的研究进展[J].中草药,2005,36(4):614-616. 被引量:30
  • 5Wagner H.Interactions between bacterial CpG-DNA and TLR9 bridge innate and adaptive immunity[J].Curr Opin Microbiol,2002,5(1):62-69.
  • 6Schlaepfer E,Audigé A,von Beust B,et al.CpG oligodeoxynucleotides block human immunodeficiency virus type 1 replication in human lymphoid tissue infected ex vivo[J].J Virol,2004,78 (22):12344-12354.
  • 7Ahmad Nejad P,Hacker H,Ruts MP,et al.Bacterial CpG-DNA and llpoploysaccharides activate Toll-like receptors at distinct cellularcompartments[J].Eur J Immunol,2002,32(7):1958-1968.
  • 8Sundstrum JB,Little DM,Villinqer F,et al.Singaling through Toll-like receptor triggers HIV-1 replication in latently infected mast cells[J].Immunology,2004,172 (7):4391-4401.
  • 9Field AK.Oligonucleotides as inhibitors of human immunodeficieocy virus[J].Curr Opin Mol Ther,1999,1(3):323-331.
  • 10Beignon AS,McKenna K,Skobene M,et al.Endocytosis of HIV-1activates plasmacytoid dendritic cells via Toll-like receptor-viral RNA interactions[J].J Clin Invest,2005,115 (11):3265-3275.

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