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维生素E对Aβ_(1-42)诱导N2a细胞凋亡的保护作用 被引量:3

Protective effects of vitamin E against N2a cell apoptosis induced by β-amyloid peptide1-42
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出处 《中国药理学通报》 CAS CSCD 北大核心 2010年第6期836-837,共2页 Chinese Pharmacological Bulletin
基金 国家自然科学基金资助项目(No10975002)
关键词 阿尔采末病 维生素E AΒ1-42 细胞凋亡 线粒体 Alzheimer's disease vitamin E Aβ1-42 apoptosis mitochondria
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  • 1Zhang Z X,Zahner G E,Roman G C,et al.Dementia subtypes in China:prevalence in Beijing,Xian,Shanghai,and Chengdu[J].Arch Neurol 2005;62(3):447-53.
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  • 3Cho D H,Nakamura T,Fang J,et al.S-nitrosylation of Drp1 mediates Aβ-related mitochondrial fission and neuronal injury[J].Science 2009,324:102-5.
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  • 5Dai X L,Sun Y X,Jiang Z F.Protective effects of vitamin E against oxidative damage Induced by Aβ1-40Cu(Ⅱ) Complexes[J].Acta Biochimica et Biophysica Sinica.2007,39(2):123-30.
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  • 7Li X M,Zhang Q Y,Cai L M,et al.Inhibitor of growth 4 induces apoptosis in human lung adenocarcinoma cell line A549 via Bcl-2 family proteins and mitochondria apoptosis pathway[J].J Cancer Res Clin Oncol.2009,135:829-35.

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