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酶联免疫法检测脑脊液阿拉伯糖甘露糖脂抗体诊断结核性脑膜炎 被引量:21

Detection of lipoarabinomannan IgG in cerebrospinal fluid with enzyme linked immunosorbent assay for diagnosis of tuberculous meningitis
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摘要 目的评估检测阿拉伯糖甘露糖脂抗体(LAMIgG)对结核性脑膜炎的诊断价值。方法应用酶联免疫吸附试验检测脑脊液中的LAMIgG。结果73例结核性脑膜炎LAMIgG阳性率为51%,36例对照组均呈阴性结果,特异性为100%。结论检测脑脊液中LAMIgG对诊断结核性脑膜炎有较高的应用价值。 Objective To ascertain the value of lipoarabinomannan IgG(LAM IgG) determination in the diagnosis of tuberculous meningitis. Methods LAM IgG in cerebrospinal fluid was detected with enzyme linked immunosorbent assay. Results The positive rate of LAM IgG in 73 patients with tuberculous meningitis was 51%, 36 control cases were all negtive. The specificity was 100%. Conclusions Detection of LAM IgG in cerebrospinal fluid is a useful tool for diagnosis of tuberculous meningitis.
出处 《中华结核和呼吸杂志》 CSCD 北大核心 1999年第1期57-58,共2页 Chinese Journal of Tuberculosis and Respiratory Diseases
关键词 结核性脑膜炎 诊断 ELISA 脑脊液 LAM-IGG Tuberculosis meningeal Cerebrospinal fluid Enzyme linked immunosorbent assay Lipoarabinomannan Antibody
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