摘要
目的 评价社区老年糖尿病与认知功能障碍之间的关系及影响因素.方法 在宣武区社区居民健康体检管理档案中,随机抽取符合2型糖尿病诊断标准的糖尿病患者308例,其中单纯糖尿病144例,糖尿病合并高血压164例,作为研究对象,并随机抽取了225例高血压病和186例相同年龄段及性别的社区健康老人作为对照组,进行MMSE测查,根据DSM-IV痴呆诊断标准及轻度认知功能障碍（MCI）诊断标准分为认知功能正常组、MCI组及痴呆组.结果 单纯糖尿病组MMSE评分低于正常对照组（25.87±3.33 vs 26.86±2.82,F=9.62,P〈0.01）,糖尿病合并高血压组MMSE评分（24.68±4.36）明显低于正常对照组（F=37.16,P〈0.01）.结论 老年糖尿病与认知功能障碍之间存在正相关,糖尿病是老年人痴呆的危险因素.糖尿病合并高血压时,可加重认知功能障碍.
Objective To evaluate the relationship between aged diabetes mellitus and cognitive impairment in community elders.Method 308 type Ⅱ diabetic patients, including 225 diabetes patients and 164 diabetes with hypertension patients, were random selected in our study. 225 hypertension and 186 healthy elders were random selected as controls. Mini-Mental State Examination （MMSE） was tested on each case. According to DSM-IV, all participants were classified into three groups （ normal, MCI and dementia） .Result MMSE scores in diabetes patients were lower than that in healthy controls（25. 87±3.33 vs 26. 86 ±2. 82, F = 9.62, P 〈 0. 01）, and scores in diabetes with hypertension group （24. 68 ±4. 36 ） were much lower than that in healthy controls （ F =37. 16, P 〈0.01）. Conclusion Senile diabetes were positive correlated with cognitive impairment. Diabetes were a risk factor of dementia in seniles. Diabetes with hypertension can increase cognitive impairment in community elders.
出处
《中国医师杂志》
CAS
2010年第5期585-587,共3页
Journal of Chinese Physician
基金
首都医学发展科研基金项目（2007-3197）
