摘要
以人参皂甙（Ｇｉｎｓ）为阳性对照，采用ＳＭＵＰ１６０心功能测定软件观察了绞股蓝皂甙（Ｇｙｐｓ）对正常大鼠基础心功能的影响和大鼠实验性心肌缺血心脏收缩功能的保护作用。结果显示，Ｇｙｐｓ对实验大鼠左室收缩功能无明显影响，但可显著拮抗大鼠急性心肌缺血所致心脏收缩功能的降低。提示Ｇｙｐｓ可明显改善实验性大鼠心肌缺血心脏的收缩功能。
The effect of Gypenosides (Gyps) on left ventricular constriction in rats with experimental myocardial ischemia was investigated in comparison with that of Ginsenosides(Gins) with using cardiac function determining software SMUP 160. The results indicated that Gyps had no effect on the basal cardiac constriction but could significantly counteract acute ischemia induced decreases of LVSP,+dp/dtmax,Vpm and Vmax compared with normal saline control ( P <0.05 or P <0.01). The results suggested that Gyps had similar protective effect on left ventricular constriction during acute myocardial ischemia to Gins in rats.
出处
《山东医科大学学报》
1999年第1期31-33,共3页
Acta Academiae Medicinae Shandong
关键词
绞股蓝皂甙
心肌缺血
心肌收缩功能
Gypenosides
Ginsenosides
Myocardial ischemia
Myocaraial constriction
Rats, inbred strains
