摘要
我院自1984年2月～1992年2月采用体外配合腔内放疗及盒式四野外放疗两种方式治疗子宫颈癌,现已随访5年以上。目的是判明两种方式的治疗效果及生存质量。体外配合腔内放疗先给盆腔前后大野外放疗46Gy,此后中间挡铅4cm外照射14～20Gy同时每周后装腔内放疗一次(当日不做外照射)A点18～24Gy。盒式四野外放疗采用盆腔前后野及两侧野共四野外放疗轮照总剂量60～65Gy,然后缩野外照射10～12Gy。结果:两组的5年生存率各为77%、51%;2年局部及盆腔病灶复发率各为125%、30%;2年远处转移率各为175%、37%;5年后的各种并发症百分率等均有显著差异(P<001～005)。体外配合腔内放疗治疗子宫颈癌其治疗效果及生存质量显著优于盒式四野外放疗。
From February 1984 to February 1992,treated on Carcinoma of Cervix with two radiotherapeutic methods (intracavitary plus extrinsic radiotherapy and extrinsic radiotherapy on four spots in box form) and followed up 5 years after the therapy.Aim is to compare the therapeudic effects and survival qualities beween the two methods.Intracavitary plus extrinsic radiotherapy adheres to the following major steps:first conduct broad exlrinsic radiotherapy 46 Gy and back parts of the pelvic cavity;then make on extrinsic radiotherapy 14～20 Gy with a lead plate of 4cm thick standing beween;at the same time perform intracavitrary after loading irradiation 18～24 Gy at point A every week (no extrinsic radiotherapy on the every day).Extrinsic radiotherapy on four spots in box form makes extrinsic therapy on the front and back parts and two sides of the pelvic cavity in turn with a total dosage of 60～65 Gy;then conduct narrow scopic extrinsic therapy 10～12 Gy.The results showed that 5 years survival rate are each 77% and 51%;the rates of the recurrence of partial and whole pelvis cavity focuses after 2 years are each 12 5% and 30%;the rates of transpers after 2 years are each 17 5% and 37% the rates of the each complications after 5 years in two groups between are significant differences ( P <0 01～0 05).We suggest that.
出处
《肿瘤防治研究》
CAS
CSCD
北大核心
1999年第2期142-143,共2页
Cancer Research on Prevention and Treatment
关键词
子宫颈癌
后装腔内放疗
放射疗法
四野外放疗
Carcinoma of Cervix
Radiotherapy
Intracavilary Afterloading irradiation
