摘要
在2×2的因子试验中用200羽1日龄艾线因肉仔鸡研究了不同硒碘营养水平对甲状腺的相对重量及其碘含量、组织硒含量及谷脱甘肽过氧化物酶和5’-脱碘酶活力、血清甲状腺激素（T4，T3）浓度的影响。试验结果表明4周龄肉仔鸡甲状腺的相对质量及碘含量因碘营养缺乏而分别显著增大和下降，但不受硒营养水平的影响；硒营养缺乏使肝脏、肾脏、心脏和胰脏硒含量及肝、肾脏谷脱甘肽过氧化物酶和5’-脱碘酶活力极显著下降；血清T4浓度因硒缺乏而上升但变化幅度未达到显著水平（P＞0．05），而且因碘缺乏而显著下降（P＜0．05）；血清T3浓度只在硒碘双重缺乏时极显著下降（P＜0．01）。在晒营养缺乏时，碘营养缺乏导致组织硒含量、肝脏和肾脏中谷脱甘肽过氧化物酶和5’-脱碘酶活力均显著下降；但在适宜的硒营养状态下，三者的下降幅度未达到显著水平（P＞0．05）。本研究结果证明肉仔鸡的硒碘营养互作关系：①5’-脱碘酶是硒酶，硒为甲状腺激素正常代谢所必需；②碘营养水平影响组织中硒沉积和硒酶活力。
In a 2 × 2 factorial experiment, 200 one-day-old broiler chicks were used to studythe effects of different selenium and iodine nutritional status on the relative weight of thyroidglands and their iodine contents, concentrations of selenium and activities of glutathione per-oxidase and 5'-iodothyronine deiodinase in some tissues, and sera thyroxine and thyroninelevels. The results showed that, thyroidal relative weights of four-week-old broiler chickswere increased but the iodine concentrations were decreased by iodine deficiency, but be notinfluenced by selenium. Selenium deficiency lowered the selenium concentrations in livers,kidneys, hearts and pancreases, and the hepatic and renal glutathione peroxidase and 5'-iodothyronine deiodinase activities significantly. Sera thyroxine levels declined significantlydue to iodine deficiency(P<0. 05), but did not elevate significantly due to selenium deficien-cy no matter what the iodine nutritional status was. The sera thyronine levels declined sig-nificantly only under concomitant selenium and iodine deficiency(P<0. 01). Under seleniumnutritional deficiency, iodine deficiency caused the selenium concentrations in the liver,kidney, heart and pancreas, and the hepatic and renal glutathione peroxidase and 5'-iodothy-ronine deiodinase activities lowered (P<0.05), but under normal selenium nutritional sta-tus, the decreased magnitutes of hepatic and renal 5'IDI activities and selenium concentra-tions and the hepatic GSHPx activity did not reach statistical significant level (P>0.05). Itcan be concluded that nutritional interrelationship between selenium and iodine does exist inbroiler chicks. On the one hand, normal thyroid hormone metabolism necessitate seleniumbecause of selenium-containing 5'-iodothyronine deiodinase; on the other hand, iodine nutri-tional status influences tissue selenium depositions and thus the activities of selenoenzymes.
出处
《中国农业大学学报》
CAS
CSCD
北大核心
1999年第1期97-101,共5页
Journal of China Agricultural University
基金
国家自然科学基金!39200086
关键词
肉仔鸡
硒
碘
鸡
营养
broiler chick
selenium
iodine
