摘要牙本质胞外基质由90％胶原(主要为Ⅰ型)和10％非胶原蛋白(non-collagenous proteins,NCPs)构成。其中胶原为羟基磷灰石(hydroxyapatite,HA)板状晶体(plate like crystalline)的沉积提供支架,NCPs则被认为控制晶体沉积的启动和生长。研究NCPs中各组分在牙本质矿化中的作用,对阐明牙齿发育及修复的分子学机制有着重要意义。
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