摘要
目的探讨人免疫缺陷病毒(HIV)合并丙型肝炎病毒(HCV)和/或乙型肝炎病毒(HBV)患者死亡原因,分析HCV和/或HBV协同感染对HIV感染者最终结局的影响。方法对某院收治的36例住院死亡的HIV感染者(其中合并HCV和/或HBV感染者26例)的主要并发症及死亡原因进行分析。结果死于呼吸衰竭和中枢神经系统疾病者在单纯HIV感染者中分别占50.00%(5/10)和30.00%(3/10),在合并HCV和/或HBV感染者中分别占50.00%(13/26)和23.08%(6/26),两组比较,差异无显著性(P>0.05)。单纯HIV感染者中未见死于肝衰竭者;合并HCV和/或HBV感染者中死于终末期肝病者6人,占合并HCV和/或HBV感染者的23.08%。结论肺部感染及中枢神经系统疾病仍是导致艾滋病患者死亡的主要原因,同样也是HIV合并HCV和/或HBV感染者的主要死亡原因。另外,也应重视防治病毒性肝炎导致的肝脏损害。
Objective To study the causes of death among HIV/AIDS patients coinfected with HCV and/or HBV,and analyse the impact of coinfection on the prognosis of HIV/AIDS patients. Methods The main complications and causes of death among 36 HIV/AIDS patients（including 26 HCV and/or HBV co-infected patients ）hospitalized in a hospital were analysed. Results Among simple HIV infected patients , 50. 00%（5/10） died of respiratory failure,30. 00%（3/10）died of central nervous system diseases, among patients coinfected with HCV and/or HBV, 51）% （13/26） died of respiratory failure, 23.08% （6/26） died of central nervous system diseases, there was no significant difference between two groups. No one died of liver function failure among simple HIV patients; 6 patients coinfected with HCV and/or HBV died of end stage liver disease , which accounting for 23.08 % of HCV and/ or HBV coinfected patients. Conclusion Pulmonary infection and central nervous system diseases are the main causes of death in AIDS patients, and is the same causes of death in HIV/AIDS patients coinfected with HCV and/or HBV.
出处
《中国感染控制杂志》
CAS
2010年第3期179-181,185,共4页
Chinese Journal of Infection Control
关键词
人免疫缺陷病毒
肝炎病毒
乙型
肝炎病毒
丙型
混合感染
艾滋病
human immunodeficiency virus
hepatitis B virus
hepatitis C virus
coinfection
acquired immunodeficiency syndrome
