摘要
在水溶液中盐酸环丙沙星与荧光桃红形成荷移络合物。离心分离后，将络合物溶于乙醇溶液中进行光度测定，络合物的最大吸收波长为５４６ｎｍ，盐酸环丙沙星的量浓度在０．５～６×１０－５ｍｏｌ／Ｌ符合比尔定律，ε＝２．７１×１０４。测定了片剂中盐酸环丙沙星的含量。
A sensitive centrifugation spectrophotometric method was developed for the determination of ciporfloxacin hydrochloride (CPFX).CPFX can react with phloxine to form a precipitate of charge transfer complex with a composition of 1∶2 by molar ratio and Job's methods.The precipitate was centrifuged and dissolved in aqueous alcohol.It showed an absorption peak at 546nm with a molar absorptivity of 2.71×10 4L·mol -1 ·cm -1 .Beer's law was obeyed in the range of 0～22 1mg/L of CPFX.The presented method has been applied to the determination of CPFX in tablets.
出处
《分析试验室》
CAS
CSCD
1999年第1期46-49,共4页
Chinese Journal of Analysis Laboratory
基金
桂林工学院青年科技基金
关键词
盐酸环丙沙星
光度法
荷移反应
测定
Ciporfloxacin hydrochloride
spectrophotometry
centrifugation
charge transfer reaction
