摘要
[目的]探讨青年人胃癌的临床病理特点。[方法]回顾性分析1999年1月至2008年12月青年人(35岁以下)胃癌的临床病理资料,并与同期180例老年人(≥75岁)的临床病理资料对比分析。[结果]35岁以下青年人胃癌占全部胃癌的5.4%,男女比例0.56∶1。肿瘤最常见位置为胃下1/3;Bormann分型以溃疡型和浸润溃疡型为主。93.6%胃癌病理类型为低分化癌、黏液腺癌和印戒细胞癌;Ⅲ～Ⅳ期占64.2%。19.7%患者一级亲属有胃癌家族史。与75岁以上老年人胃癌相比,性别比例、肿瘤位置、肿瘤分化和胃癌家族史等方面有明显差异。[结论]青年人胃癌恶性程度高,应加强青年人胃癌的早期诊断和治疗研究,以期提高预后。
[Purpose] To investigate the clinicopathological characteristics of gastric cancer in young patients. [Methods] Clinicopathological characteristics of 187 young （≤35 years old） patients with gastric cancer from January,1999 to December,2008 were retrospectively analyzed,and compared to 180 elderly （≥75 years old） cases with gastric cancer.[Results] Young gastric cancer accounted for 5.4% of all gastric cancer patients during the study peri-od. The ratio of male and female was 0.56∶1. The tumors occurred most often in lower one-third of stomach. Ulcerated and ulcerated infiltrating types were the most common type in Bormann classification. Poorly differentiated adenocarcinoma,mucinous adenocarcinoma and signet ring cell carcinoma were present in 93.6%. 64.2% of the patients present with stage Ⅲ or Ⅳ. 19.7% patients had a positive gastric cancer family history for the first degree rela-tives. Compared with elderly patients,there was significant differences in sex ratio,tumor lo-cation,differentiation and family gastric cancer history. [Conclusion] Gastric cancer in young patients have higher malignant behavior. Early diagnosis and treatment must be strengthened to improve the prognosis.
出处
《肿瘤学杂志》
CAS
2010年第5期377-379,共3页
Journal of Chinese Oncology
关键词
胃肿瘤
临床病理
青年人
gastric neoplasms
clinicopathological characteristics
younger
