摘要
目的探讨连续静脉输注硫酸镁治疗成人重症破伤风的有效性和安全性。方法回顾性分析2007年5月至2009年6月收治的重症破伤风患者19例，经静脉输注硫酸镁辅以安定和氯丙嗪，以控制患者肌肉强直和抽搐，控制自律性不稳定。结果19例患者全部治愈，其中仅5例需要加用肌松剂和机械通气，无并发症发生。结论硫酸镁可有效控制重症破伤风患者的临床症状，并减少其他镇静剂的用量，简化护理程序，并发症少，总体费用低且给药方便。
Objective To investigate the efficacy and safety of continuous intravenous infusion of magnesium sulphate for the treatment of severe tetanus in adults. Methods The clinical data of 19 patients with severe tetanus between May 2007 and June 2009 in the Department of General Surgery of the Affiliated Hospital of Jianghan University were analyzed retrospectively. Magnesium sulphate（ i. v. ）in combination with diazepam and chloropromazine was used to control spasticity, spasms and autonomic dysfunction. Results All the nineteen patients were cured. Only five patients were given additionally neuromuscular blocking drugs and ventilating support. And no complications occurred. Conclusion Magnesium sulphate therapy can control the symptom of severe tetanus effectively, reduce the requirement for other drugs to control muscle spasms, simplify nursing care and reduce the complications.
出处
《临床外科杂志》
2010年第4期262-264,共3页
Journal of Clinical Surgery
关键词
成人
重症破伤风
硫酸镁
adults
severe tetanus
magnesium sulphate
