摘要
目的:通过分析子宫内膜癌临床病理资料,探讨影响子宫内膜癌预后的因素。方法:回顾性分析112例子宫内膜癌患者的临床病理资料,采用Cox比例风险回归模型研究与预后相关因素。结果:初始治疗为手术治疗的子宫内膜癌患者112例,总生存率为87.1%。单因素分析显示,是否绝经、组织学类型与子宫内膜癌的局部复发有关,而肌层浸润深度、宫颈侵犯与否及是否绝经和总体存活有关。Cox多变量回归分析显示,细胞学分级、组织学类型与子宫内膜癌的复发有关,宫颈是否侵犯与总体存活有关。结论:子宫内膜癌预后良好,应系统评估患者预后因素,实行个体化的治疗方案。
Objective To explore the prognostic factors in endometrial cancer with analysis of endometrial cancer clinical and pathological data.Methods 112 patients of endometrial carcinoma were treated in our hostipal.The clinical and pathological data were analyzed retrospectively.Using Cox proportional hazard regression analysis to evaluate the factors related to overall survival and local recurrence.Results 112 patients with endometrial carcinoma were treated initially by surgeries,the overall survival rate was 87.1%.Univariate analysis demonstrated that the menopause,histological type and the risk factors had a significant effect on local relapse.The uterus-muscle involvement,cervical invasion and menopause had a significant effect on overall survival.In the multivariate analysis,cytology classification,histological type were prognostic factors for local relap se and cervical invasion was prognostic factor for overall survival.Conclusion Endometrial cancer prognosis is very good,should be systematically assessed with prognostic factors.In order to improve the prognosis of the patients in endometrial carcinoma,they should be treated by individual therapies.
出处
《吉林医学》
CAS
2010年第15期2174-2175,共2页
Jilin Medical Journal
关键词
子宫内膜癌
预后
复发
总体存活
Endometrial cancer
Prognosis
Recurrence
Overall survival