摘要
目的：探讨血小板的活化在腰椎间盘突出症中的作用和康复治疗对血小板活化的影响。方法：采用双抗体夹心ＥＬＩＳＡ法测定２０例腰椎间盘突出症患者康复治疗前后和１８名正常人血浆内血小板α－颗粒膜蛋白１４０（ＧＭＰ－１４０）含量。结果：腰椎间盘突出症患者血浆ＧＭＰ－１４０水平显著高于正常对照组（Ｐ＜０．００１），康复治疗后血浆内ＧＭＰ－１４０水平比治疗前明显降低（Ｐ＜０．００１），但仍高于正常对照组（Ｐ＜０．０５）。结论：腰椎间盘突出症的发病与ＧＭＰ－１４０有关。
Objective:To study the effect of platelet activation to lumbar intervertebral disc prolapse(LIDP) and the influence of rehabilitation therapy on plateled activation.Methods:The plasma levels of granule membrane protein 140(GMP-140) before and after rehabilitation therapy on the 20 cases of LIDP were investigated by Two-layer antibody sandwich enzyme-linked immunosorbent assay(ELISA) method.Rusults:The plasma levels of GMP-140 was significantly higher in LIDP (7.17±3.8)μg/ml than in control group(P<0.001).After treatment,the levels of GMP-140 were significantly lower than those of pre-treatment(P<0.001),buthigher than the control group(P<0.05).Conclusion:The LIDP was correlated with GMP-140.The rehabilitation therapy can reduce and inhibit the platelet activation.
出处
《中华理疗杂志》
1999年第1期20-21,共2页
Chinese Journal of Physical Therapy
关键词
腰椎
椎间盘突出
康复疗法
血小板活化
Traction Massage Exercise therapy Intervertebral disk displacement,lumbar Platelet activation
